The last decade has witnessed an explosion of studies evaluating the impact of the human
microbiota on a variety of disease states. The microbiota can impact diseases in multiple …

We are beginning to appreciate the complex relationship between the gut microbiome and
host immune regulation and dysregulation in health and disease. Potentially important …

In most chronic inflammatory diseases, the cause remains unknown. Chronic infection is,
however, among the current hypotheses. Recent technological advances have allowed in …

The human microbiome, which represents the total collection of microorganisms (and their
genes) inhabiting the human body, has increasingly been recognized as a potential key …

The intestinal microbiota is firmly implicated not only in the pathogenesis of inflammatory
bowel disease (IBD) but increasingly also in the development of inflammation at …

A causal link between the wealth of microbes that populate our body surfaces, designated
as microbiota, and inflammatory disorders, including ankylosing spondylitis and the related …

Spondyloarthritis (SpA) encompasses a group of diseases characterized by an inflammatory
arthritis involving both joints and entheses. However, extraarticular symptoms constitute a …

Humans and microbes have developed a symbiotic relationship over time, and alterations in
this symbiotic relationship have been linked to several immune mediated diseases such as …

In higher vertebrates, mucosal sites at the border between the internal and external
environments, directly interact with bacteria, viruses, and fungi. Through co-evolution, hosts …

Our commensal microbial communities respond to changes in our health, and are altered in
people with arthritis. Understanding the complex relationships between the microbiota and …