Niacin, as an antidyslipidemic drug, elicits a strong flushing response by release of
prostaglandin (PG) D2. However, whether niacin is beneficial for inflammatory bowel …

Butyrate and niacin are produced by gut microbiota, however butyrate has received most
attention for its effects on colonic health. The present study aimed at exploring the effect of …

Ulcerative Colitis (UC) is a major form of chronic inflammatory bowel disease of the colonic
mucosa and exhibits progressive morbidity. There is still a substantial need of small …

Aim Ulcerative colitis (UC) is a common intestinal problem characterized by the diffusion of
colon inflammation and immunity dysregulation. Nifuroxazide, a potent STAT-3 inhibitor …

Similar to canine inflammatory enteropathy, inflammatory bowel disease (IBD) is a chronic
idiopathic condition characterized by remission periods and recurrent flares in which …

ABSTRACT Cyclooxygenase‐2 (COX‐2) has long been implicated in the pathogenesis of
inflammatory bowel diseases (IBDs). COX‐2 is mostly known for the production of …

Immunological tolerance is critical for maintaining gut homeostasis. An imbalance between
interleukin-17 (IL-17)-producing T helper 17 (TH 17) cells and regulatory T cells (T reg cells) …

Ulcerative colitis is a recrudescent intestinal inflammation coupled with diarrhea, weight
loss, pus, and blood stool, which seriously impacts the quality of patient life. D-Pinitol, which …

Ulcerative colitis (UC) is a disease characterized by inflammation and disruption of the
intestinal epithelial barrier. Necroptosis plays a critical role in disease progression. Indole-3 …

Context Ulcerative colitis (UC) is a common acute or chronic intestinal disease with an
imbalance of inflammation. Picroside II (P-II) exerts a protective role in various inflammation …