Glycosylation occurs at all major types of biomolecules, including proteins, lipids, and RNAs
to form glycoproteins, glycolipids, and glycoRNAs in mammalian cells, respectively. The …

Simple Summary Glycosylation is one of the most pivotal post-translational modifications on
all types of biomolecules for the formation of glycoproteins, glycolipids, and glycoRNAs in a …

Glycosylation is the most complex post-translational modification of proteins. Altered glycans
on the tumor-and host-cell surface and in the tumor microenvironment have been identified …

Glycomic profiling of tumour tissues consistently shows alterations in N-and O-glycosylation
profiles of glycoproteins and glycolipids compared to healthy tissues, with important …

Glycans represent a vast class of molecules that modify either proteins or lipids. They exert
and regulate important and complex functions in both normal and cancer cell metabolism …

Simple Summary Aberrant glycosylation is a common feature of many cancers, and it plays
crucial roles in tumor development and biology. Cancer progression can be regulated by …

Changes in cell surface glycosylation are a hallmark of the transition from normal to inflamed
and neoplastic tissue. Tumor-associated carbohydrate antigens (TACAs) challenge our …

A link between cancer and aberrant glycosylation has recently become evident. Glycans and
their altered forms, known as tumour-associated carbohydrate antigens (TACAs), are …

Glycosylation and its by-product, the glycan, play a crucial role in many cellular processes.
Aberrant glycan structures and mutations of the glycosylation pathway have been intricately …

Aberrant expression of glycosphingolipids (GSLs) is a unique feature of cancer and stromal
cells in tumor microenvironments. Although the impact of GSLs on tumor progression …