Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?

RG Jensen, HK Johansen, T Bjarnsholt… - European Archives of …, 2017 - Springer
Dispersal of bacteria from a biofilm in the middle ear, serving as a bacterial reservoir, could
explain the recurrent and chronic nature of chronic suppurative otitis media (CSOM). The …

Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media

P Homøe, T Bjarnsholt, M Wessman… - European Archives of …, 2009 - Springer
Biofilm may explain the recurrences and recalcitrant episodes of otorrhea in chronic
suppurative otitis media (CSOM). This study investigates bacterial biofilm in Greenlanders …

Multi-species bacterial biofilm and intracellular infection in otitis media

RB Thornton, PJ Rigby, SP Wiertsema, P Filion… - BMC pediatrics, 2011 - Springer
Background Bacteria which are metabolically active yet unable to be cultured and
eradicated by antibiotic treatment are present in the middle ear effusion of children with …

Mucosal biofilm detection in chronic otitis media: a study of middle ear biopsies from Greenlandic patients

M Wessman, T Bjarnsholt… - European Archives of …, 2015 - Springer
The objectives of this study were to examine middle ear biopsies from Greenlandic patients
with chronic otitis media (COM) for the presence of mucosal biofilms and the bacteria within …

[PDF][PDF] Microbiology of chronic suppurative otitis media, study of the role of bacterial biofilm and fungal infection

IA Abdelshafy, AA Haleem, YA Khalil… - J Otolaryngol ENT …, 2015 - academia.edu
Chronic suppurative otitis media (CSOM) is defined as chronic inflammation of middle ear
cleft. The disease is common in all age groups but more prevalent in low socioeconomic …

[PDF][PDF] Microbiology of chronic suppurative otitis media: a prospective study in a tertiary care hospital

S Balan, B Viswanatha - J Otolaryngol ENT Res, 2017 - researchgate.net
Materials and methods The present study was conducted among patients with CSOM who
attended Outpatient department of a tertiary care institute for a period of 1 year from July …

Detection of bacterial biofilms in different types of chronic otitis media

X Gu, Y Keyoumu, L Long, H Zhang - European Archives of Oto-Rhino …, 2014 - Springer
Biofilms are organized bacterial communities that may be homogeneous or heterogeneous.
They play a significant role in the pathogenesis of chronic nasal sinusitis, chronic tonsillitis …

Evaluation of the current bacteriological profile and antibiotic sensitivity pattern in chronic suppurative otitis media

WNA Wan Draman, MK Md Daud… - Laryngoscope …, 2021 - Wiley Online Library
Objective To determine the current microbiological profile of chronic suppurative otitis media
(CSOM), their antimicrobial sensitivity, their resistance pattern to locally available antibiotics …

Microbiological profile of chronic supurative otitis media

BL Shrestha, RCM Amatya, I Shrestha… - Nepalese Journal of ENT …, 2011 - njehns.org.np
Objective: To observe the frequency of different micro-organisms of Chronic suppurative
otitis media (CSOM). Materials and Methods: This was the prospective, randomized and …

Topical therapy failure in chronic suppurative otitis media is due to persister cells in biofilms

PL Santa Maria, AC Kaufman, B Bacacao… - Otology & …, 2021 - journals.lww.com
Objective: Chronic suppurative otitis media (CSOM) is characterized by a chronically
draining middle ear. CSOM is typically treated with multiple courses of antibiotics or …