Cancer immunotherapy has revolutionized cancer treatment, and it relies heavily on the
comprehensive understanding of the immune landscape of the tumor microenvironment …

The tumor microenvironment is a highly complex ecosystem of diverse cell types, which
shape cancer biology and impact the responsiveness to therapy. Here, we analyze the …

Esophageal cancer (EC) seriously threatens human health, and a promising new avenue for
EC treatment involves cancer immunotherapy. To improve the efficacy of EC immunotherapy …

The tumor microenvironment (TME) is connected to immunotherapy responses, but it
remains unclear how cancer cells and host tissues differentially influence the immune …

Esophageal squamous cell carcinoma (ESCC) is prevalent in some geographical regions of
the world. ESCC development presents a multistep pathogenic process from inflammation to …

Esophageal squamous-cell carcinoma (ESCC), one of the most prevalent and lethal
malignant disease, has a complex but unknown tumor ecosystem. Here, we investigate the …

Lymph node metastasis, the leading cause of mortality in esophageal squamous carcinoma
(ESCC) with a highly complex tumor microenvironment, remains underexplored. Here, the …

The tumor microenvironment (TME) is an integral part of cancer. Recognition of the essential
nature of the TME in cancer evolution has led to a shift from a tumor cell-centered view of …

The recent development of immunotherapy as a cancer treatment has proved effective over
recent years, but the precise dynamics between the tumor microenvironment (TME) …

Esophageal squamous cell carcinoma (ESCC) is the main prevalent histological type of
esophageal cancer, predominantly constituting 90% of cases worldwide. Despite the …