Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment
Y Zheng, Z Chen, Y Han, L Han, X Zou, B Zhou… - Nature …, 2020 - nature.com
Cancer immunotherapy has revolutionized cancer treatment, and it relies heavily on the
comprehensive understanding of the immune landscape of the tumor microenvironment …
comprehensive understanding of the immune landscape of the tumor microenvironment …
Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment
The tumor microenvironment is a highly complex ecosystem of diverse cell types, which
shape cancer biology and impact the responsiveness to therapy. Here, we analyze the …
shape cancer biology and impact the responsiveness to therapy. Here, we analyze the …
The immune landscape of esophageal cancer
TX Huang, L Fu - Cancer communications, 2019 - Springer
Esophageal cancer (EC) seriously threatens human health, and a promising new avenue for
EC treatment involves cancer immunotherapy. To improve the efficacy of EC immunotherapy …
EC treatment involves cancer immunotherapy. To improve the efficacy of EC immunotherapy …
Immune phenotypic linkage between colorectal cancer and liver metastasis
Y Liu, Q Zhang, B Xing, N Luo, R Gao, K Yu, X Hu, Z Bu… - Cancer cell, 2022 - cell.com
The tumor microenvironment (TME) is connected to immunotherapy responses, but it
remains unclear how cancer cells and host tissues differentially influence the immune …
remains unclear how cancer cells and host tissues differentially influence the immune …
Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer
Esophageal squamous cell carcinoma (ESCC) is prevalent in some geographical regions of
the world. ESCC development presents a multistep pathogenic process from inflammation to …
the world. ESCC development presents a multistep pathogenic process from inflammation to …
Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis
Esophageal squamous-cell carcinoma (ESCC), one of the most prevalent and lethal
malignant disease, has a complex but unknown tumor ecosystem. Here, we investigate the …
malignant disease, has a complex but unknown tumor ecosystem. Here, we investigate the …
Single‐cell transcriptomic analysis of primary and metastatic tumor ecosystems in esophageal squamous cell carcinoma
Y Jia, B Zhang, C Zhang, DLW Kwong… - Advanced …, 2023 - Wiley Online Library
Lymph node metastasis, the leading cause of mortality in esophageal squamous carcinoma
(ESCC) with a highly complex tumor microenvironment, remains underexplored. Here, the …
(ESCC) with a highly complex tumor microenvironment, remains underexplored. Here, the …
[HTML][HTML] Targeting the tumor microenvironment: removing obstruction to anticancer immune responses and immunotherapy
JM Pitt, A Marabelle, A Eggermont, JC Soria… - Annals of …, 2016 - Elsevier
The tumor microenvironment (TME) is an integral part of cancer. Recognition of the essential
nature of the TME in cancer evolution has led to a shift from a tumor cell-centered view of …
nature of the TME in cancer evolution has led to a shift from a tumor cell-centered view of …
Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses
The recent development of immunotherapy as a cancer treatment has proved effective over
recent years, but the precise dynamics between the tumor microenvironment (TME) …
recent years, but the precise dynamics between the tumor microenvironment (TME) …
Tumor immune microenvironment and immune checkpoint inhibitors in esophageal squamous cell carcinoma
Y Baba, D Nomoto, K Okadome, T Ishimoto… - Cancer …, 2020 - Wiley Online Library
Esophageal squamous cell carcinoma (ESCC) is the main prevalent histological type of
esophageal cancer, predominantly constituting 90% of cases worldwide. Despite the …
esophageal cancer, predominantly constituting 90% of cases worldwide. Despite the …