Prenatal heroin exposure alters brain morphology and connectivity in adolescent mice
KJ Hornburg, LM Slosky, G Cofer, J Cook… - NMR in …, 2023 - Wiley Online Library
The United States is experiencing a dramatic increase in maternal opioid misuse and,
consequently, the number of individuals exposed to opioids in utero. Prenatal opioid …
consequently, the number of individuals exposed to opioids in utero. Prenatal opioid …
In utero methadone exposure permanently alters anatomical and functional connectivity: A preclinical evaluation
EM Chin, Y Kitase, NK Madurai, S Robinson… - Frontiers in …, 2023 - frontiersin.org
The opioid epidemic is an ongoing public health crisis, and children born following prenatal
opioid exposure (POE) have increased risk of long-term cognitive and behavioral sequelae …
opioid exposure (POE) have increased risk of long-term cognitive and behavioral sequelae …
Alterations of brain microstructures in a mouse model of prenatal opioid exposure detected by diffusion MRI
Growing opioid use among pregnant women is fueling a crisis of infants born with prenatal
opioid exposure. A large body of research has been devoted to studying the management of …
opioid exposure. A large body of research has been devoted to studying the management of …
Brain morphology in school-aged children with prenatal opioid exposure: A structural MRI study
E Sirnes, L Oltedal, H Bartsch, GE Eide, IB Elgen… - Early human …, 2017 - Elsevier
Background Both animal and human studies have suggested that prenatal opioid exposure
may be detrimental to the developing fetal brain. However, results are somewhat conflicting …
may be detrimental to the developing fetal brain. However, results are somewhat conflicting …
Prenatal opioid exposure is associated with smaller brain volumes in multiple regions
Background The impact of prenatal opioid exposure on brain development remains poorly
understood. Methods We conducted a prospective study of term-born infants with and …
understood. Methods We conducted a prospective study of term-born infants with and …
Perturbed neurochemical and microstructural organization in a mouse model of prenatal opioid exposure: A multi-modal magnetic resonance study
Methadone-based treatment for pregnant women with opioid use disorder is quite prevalent
in the clinical environment. A number of clinical and animal model-based studies have …
in the clinical environment. A number of clinical and animal model-based studies have …
Maternal opioid exposure culminates in perturbed murine neurodevelopment and hyperactive phenotype in adolescence
CR Schlagal, TJ Dunn, P Xu, DE Felsing, CR Merritt… - Neuroscience, 2021 - Elsevier
Opioid use by women during pregnancy has risen dramatically since 2004, accompanied by
a striking increase in the prevalence of neonatal opioid withdrawal syndrome (NOWS) and …
a striking increase in the prevalence of neonatal opioid withdrawal syndrome (NOWS) and …
Prenatal methadone exposure selectively alters protein expression in primary motor cortex: Implications for synaptic function
As problematic opioid use has reached epidemic levels over the past 2 decades, the annual
prevalence of opioid use disorder (OUD) in pregnant women has also increased 333%. Yet …
prevalence of opioid use disorder (OUD) in pregnant women has also increased 333%. Yet …
A Prospective Multi-Institutional Study Comparing the Brain Development in the Third Trimester between Opioid-Exposed and Nonexposed Fetuses Using Advanced …
BACKGROUND AND PURPOSE: While the adverse neurodevelopmental effects of prenatal
opioid exposure on infants and children in the United States are well described, the …
opioid exposure on infants and children in the United States are well described, the …
Neuroimaging of children following prenatal drug exposure
Recent advances in MR-based brain imaging methods have provided unprecedented
capabilities to visualize the brain. Application of these methods has allowed identification of …
capabilities to visualize the brain. Application of these methods has allowed identification of …