Rett syndrome (RTT) is an X-linked, neurodevelopmental disorder caused primarily by
mutations in the methyl-CpG-binding protein 2 (MECP2) gene, which encodes a …

MicroRNAs (miRNAs) are a class of small, noncoding RNAs that function as
posttranscriptional regulators of gene expression. Many miRNAs are expressed in the …

MicroRNAs (miRNAs) are short non-coding RNA molecules that regulate post-transcriptional
gene expression. They influence a wide range of physiological functions, including neuronal …

Mecp2 is a transcriptional repressor protein that is mutated in Rett syndrome, a
neurodevelopmental disorder that is the second most common cause of mental retardation …

Rett syndrome (RTT) is a neurodevelopmental disorder caused by MECP2 mutations.
Although emerging evidence suggests that MeCP2 deficiency is associated with …

Rett Syndrome (RTT) is a severe, rare, and progressive developmental disorder with
patients displaying neurological regression and autism spectrum features. The affected …

Abstract Background MeCP2, methyl-CpG-binding protein 2, binds to methylated cytosines
at CpG dinucleotides, as well as to unmethylated DNA, and affects chromatin condensation …

The postnatal neurodevelopmental disorder Rett syndrome (RTT) is caused by mutations in
the gene encoding methyl-CpG binding protein 2 (MeCP2), a transcriptional repressor …

A progressive increase in MECP2 protein levels is a crucial and precisely regulated event
during neurodevelopment, but the underlying mechanism is unclear. We report that MECP2 …

Proper neurological function in humans requires precise control of levels of the epigenetic
regulator methyl CpG-binding protein 2 (MeCP2). MeCP2 protein levels are low in fetal …