Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer
D Fallik, F Borrini, V Boige, J Viguier, S Jacob… - Cancer research, 2003 - AACR
The aim of our study was to assess the relationship between colorectal tumor
responsiveness to irinotecan and microsatellite instability (MSI), a feature of colorectal …
responsiveness to irinotecan and microsatellite instability (MSI), a feature of colorectal …
[HTML][HTML] Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines
E Vilar, M Scaltriti, J Balmana, C Saura… - British journal of …, 2008 - nature.com
Around 15% of colorectal cancers (CRCs) show microsatellite instability (MSI) due to
dysfunction of the mismatch repair system (MMR). As a consequence of this, MSI tumours …
dysfunction of the mismatch repair system (MMR). As a consequence of this, MSI tumours …
Microsatellite instability in the management of colorectal cancer
MS Pino, DC Chung - Expert review of gastroenterology & …, 2011 - Taylor & Francis
Microsatellite instability (MSI) is a form of genetic instability caused by alterations in the DNA
mismatch repair system. Approximately 15% of colorectal cancers display MSI due to a …
mismatch repair system. Approximately 15% of colorectal cancers display MSI due to a …
Microsatellite instability in colorectal cancer—the stable evidence
Microsatellite instability (MSI) is the molecular fingerprint of a deficient mismatch repair
system. Approximately 15% of colorectal cancers (CRC) display MSI owing either to …
system. Approximately 15% of colorectal cancers (CRC) display MSI owing either to …
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the …
CR Boland, SN Thibodeau, SR Hamilton, D Sidransky… - Cancer research, 1998 - AACR
Abstract In December 1997, the National Cancer Institute sponsored “The International
Workshop on Microsatellite Instability and RER Phenotypes in Cancer Detection and …
Workshop on Microsatellite Instability and RER Phenotypes in Cancer Detection and …
Microsatellite instability is a predictive marker for survival benefit from adjuvant chemotherapy in a population-based series of stage III colorectal carcinoma
H Elsaleh, B Iacopetta - Clinical colorectal cancer, 2001 - Elsevier
Tumors with the microsatellite instability (MSI) phenotype appear to comprise a biologically
and clinically distinct group of colorectal carcinomas (CRC). MSI+ has been associated with …
and clinically distinct group of colorectal carcinomas (CRC). MSI+ has been associated with …
Microsatellite instability and colorectal cancer prognosis
P Benatti, R Gafà, D Barana, M Marino, A Scarselli… - Clinical Cancer …, 2005 - AACR
Purpose: Many studies have evaluated the role of high levels of microsatellite instability
(MSI) as a prognostic marker and predictor of the response to chemotherapy in colorectal …
(MSI) as a prognostic marker and predictor of the response to chemotherapy in colorectal …
Microsatellite instability, prognosis and drug sensitivity of stage II and III colorectal cancer: more complexity to the puzzle
S Tejpar, Z Saridaki, M Delorenzi… - Journal of the …, 2011 - academic.oup.com
842 Editorials| JNCI Vol. 103, Issue 11| June 8, 2011 untreated stage II and stage III CRC
patients with MSI tumors showed a clearly improved rate of 5-year disease-free survival …
patients with MSI tumors showed a clearly improved rate of 5-year disease-free survival …
Microsatellite instability in colorectal carcinoma: The comparison of immunohistochemistry and molecular biology suggests a role for hMLH6 immunostaining
V Rigau, N Sebbagh, S Olschwang… - … of pathology & …, 2003 - meridian.allenpress.com
Abstract Context.—Microsatellite instability (MSI) due to defective mismatch repair (MMR)
genes has been reported in the majority of colorectal tumors from patients with hereditary …
genes has been reported in the majority of colorectal tumors from patients with hereditary …
Predictive and prognostic value of microsatellite instability in patients with advanced colorectal cancer treated with a fluoropyrimidine and oxaliplatin containing first …
CI Müller, K Schulmann, A Reinacher-Schick… - International journal of …, 2008 - Springer
Background and aims Microsatellite instability (MSI) is a potential indicator of prognosis in
patients with colorectal cancer (CRC). To date, there are a limited number of studies which …
patients with colorectal cancer (CRC). To date, there are a limited number of studies which …
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