While no single model can exactly recapitulate all aspects of multiple sclerosis (MS), animal
models are essential in understanding the induction and pathogenesis of the disease and to …

In view of disease heterogeneity of multiple sclerosis and limited access to ex vivo
specimens, different approaches must be undertaken to better understand disease …

Multiple sclerosis (MS) is an inflammatory and demyelinating condition of the CNS,
characterized by perivascular infiltrates composed largely of T lymphocytes and …

Multiple sclerosis (MS) is a multifocal demyelinating disease of the central nervous system
(CNS) leading to the progressive destruction of the myelin sheath surrounding axons. It can …

Multiple sclerosis (MS), a demyelinating disease of the central nervous system (CNS),
presents as a complex disease with variable clinical and pathological manifestations …

Although multiple sclerosis is a uniquely human disease, many pathological features can be
induced in experimental autoimmune encephalomyelitis (EAE) models following induction of …

Multiple sclerosis (MS) is a spontaneous, acquired, inflammatory demyelinating disease of
the human CNS. Because it involves a complex interaction between two of the most intricate …

Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous
system (CNS) manifested with varying clinical course, pathology, and inflammatory patterns …

Multiple sclerosis (MS) is a chronic, progressive disorder of the central nervous system
(CNS) that affects more than two million people worldwide. Several animal models resemble …

Experimental autoimmune encephalitis (EAE), the animal model of multiple sclerosis (MS),
has provided significant insight into the mechanisms that initiate and drive autoimmunity …