Insights into interplay of immunopathophysiological events and molecular mechanistic cascades in psoriasis and its associated comorbidities

AK Srivastava, TC Yadav, HK Khera, P Mishra… - Journal of …, 2021 - Elsevier
Psoriasis is an inflammatory skin disease with complex pathogenesis and multiple
etiological factors. Besides the essential role of autoreactive T cells and constellation of …

[HTML][HTML] Inflammation and psoriasis: a comprehensive review

AM Man, MS Orăsan, OA Hoteiuc… - International Journal of …, 2023 - mdpi.com
Psoriasis is an immune-mediated disease with a strong genetic component that brings many
challenges to sick individuals, such as chronic illness, and which has multiple associated …

[HTML][HTML] Molecular mechanisms and management of a cutaneous inflammatory disorder: psoriasis

YR Woo, DH Cho, HJ Park - International Journal of Molecular Sciences, 2017 - mdpi.com
Psoriasis is a complex chronic inflammatory cutaneous disorder. To date, robust molecular
mechanisms of psoriasis have been reported. Among diverse aberrant immunopathogenetic …

[HTML][HTML] Psoriasis pathogenesis and treatment

A Rendon, K Schäkel - International journal of molecular sciences, 2019 - mdpi.com
Research on psoriasis pathogenesis has largely increased knowledge on skin biology in
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …

Progress in understanding the immunopathogenesis of psoriasis

RKH Mak, C Hundhausen, FO Nestle - Actas dermo-sifiliograficas, 2009 - Elsevier
This review emphasizes how translation from bench research to clinical knowledge and vice
versa has resulted in considerable progress in understanding the immunopathogenesis of …

[HTML][HTML] Scanning the immunopathogenesis of psoriasis

A Chiricozzi, P Romanelli, E Volpe… - International journal of …, 2018 - mdpi.com
Psoriasis is a chronic inflammatory skin disease, the immunologic model of which has been
profoundly revised following recent advances in the understanding of its pathophysiology. In …

[HTML][HTML] Signaling pathways and targeted therapies for psoriasis

J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

The inflammatory response in psoriasis: a comprehensive review

Y Deng, C Chang, Q Lu - Clinical reviews in allergy & immunology, 2016 - Springer
Psoriasis is a chronic inflammatory autoimmune disease characterized by an excessively
aberrant hyperproliferation of keratinocytes. The pathogenesis of psoriasis is complex and …

Pathophysiology of psoriasis: A review

K Yamanaka, O Yamamoto… - The Journal of …, 2021 - Wiley Online Library
Psoriasis is a complex chronic inflammatory skin disease caused by the dynamic interplay
between multiple genetic risk foci, environmental risk factors, and excessive immunological …

[HTML][HTML] Therapeutic development based on the immunopathogenic mechanisms of psoriasis

JC Tseng, YC Chang, CM Huang, LC Hsu, TH Chuang - Pharmaceutics, 2021 - mdpi.com
Psoriasis, a complex inflammatory autoimmune skin disorder that affects 2–3% of the global
population, is thought to be genetically predetermined and induced by environmental and …