[HTML][HTML] Theranostic strategy of focused ultrasound induced blood-brain barrier opening for CNS disease treatment
Focused Ultrasound (FUS) in combination with gaseous microbubbles has emerged as a
potential new means of effective drug delivery to the brain. Recent research has shown that …
potential new means of effective drug delivery to the brain. Recent research has shown that …
Applications of focused ultrasound-mediated blood-brain barrier opening
The blood brain barrier (BBB) plays a critically important role in the regulation of central
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …
Noninvasive and targeted delivery of therapeutics to the brain using focused ultrasound
The range of therapeutic treatment options for central nervous system (CNS) diseases is
greatly limited by the blood-brain barrier (BBB). While a variety of strategies to circumvent …
greatly limited by the blood-brain barrier (BBB). While a variety of strategies to circumvent …
[HTML][HTML] Focused ultrasound combined with microbubbles in central nervous system applications
The blood–brain barrier (BBB) protects the central nervous system (CNS) from invasive
pathogens and maintains the homeostasis of the brain. Penetrating the BBB has been a …
pathogens and maintains the homeostasis of the brain. Penetrating the BBB has been a …
Ultrasound-mediated blood–brain barrier opening: An effective drug delivery system for theranostics of brain diseases
J Wang, Z Li, M Pan, M Fiaz, Y Hao, Y Yan… - Advanced Drug Delivery …, 2022 - Elsevier
Blood-brain barrier (BBB) remains a significant obstacle to drug therapy for brain diseases.
Focused ultrasound (FUS) combined with microbubbles (MBs) can locally and transiently …
Focused ultrasound (FUS) combined with microbubbles (MBs) can locally and transiently …
Ultrasound-mediated blood–brain barrier disruption for targeted drug delivery in the central nervous system
M Aryal, CD Arvanitis, PM Alexander… - Advanced drug delivery …, 2014 - Elsevier
The physiology of the vasculature in the central nervous system (CNS), which includes the
blood–brain barrier (BBB) and other factors, complicates the delivery of most drugs to the …
blood–brain barrier (BBB) and other factors, complicates the delivery of most drugs to the …
Secondary effects on brain physiology caused by focused ultrasound-mediated disruption of the blood–brain barrier
Focused ultrasound (FUS) combined with microbubbles is a non-invasive method for
targeted, reversible disruption of the blood–brain barrier (FUS-BBB opening). This approach …
targeted, reversible disruption of the blood–brain barrier (FUS-BBB opening). This approach …
[HTML][HTML] Submicron-bubble-enhanced focused ultrasound for blood–brain barrier disruption and improved CNS drug delivery
The use of focused ultrasound (FUS) with microbubbles has been proven to induce transient
blood–brain barrier opening (BBB-opening). However, FUS-induced inertial cavitation of …
blood–brain barrier opening (BBB-opening). However, FUS-induced inertial cavitation of …
[HTML][HTML] Characterization of different microbubbles in assisting focused ultrasound-induced blood-brain barrier opening
Microbubbles (MBs) serve as a critical catalyst to amplify local cavitation in CNS capillary
lumen to facilitate focused ultrasound (FUS) to transiently open the blood-brain barrier …
lumen to facilitate focused ultrasound (FUS) to transiently open the blood-brain barrier …
Focused ultrasound-mediated drug delivery through the blood–brain barrier
A Burgess, K Shah, O Hough… - Expert review of …, 2015 - Taylor & Francis
Despite recent advances in blood–brain barrier (BBB) research, it remains a significant
hurdle for the pharmaceutical treatment of brain diseases. Focused ultrasound (FUS) is one …
hurdle for the pharmaceutical treatment of brain diseases. Focused ultrasound (FUS) is one …
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