Malic acid production from renewables: a review

A Kövilein, C Kubisch, L Cai… - Journal of chemical …, 2020 - Wiley Online Library
Malic acid derived from fossil resources is currently applied in the food and beverage
industries with a medium global production capacity. However, in the transition from a fossil …

[HTML][HTML] Microbial biosynthesis of L-malic acid and related metabolic engineering strategies: advances and prospects

Z Wei, Y Xu, Q Xu, W Cao, H Huang… - Frontiers in Bioengineering …, 2021 - frontiersin.org
Malic acid, a four-carbon dicarboxylic acid, is widely used in the food, chemical and medical
industries. As an intermediate of the TCA cycle, malic acid is one of the most promising …

Recent advances in microbial production of L-malic acid

N Wu, J Zhang, Y Chen, Q Xu, P Song, Y Li… - Applied Microbiology …, 2022 - Springer
Over the last few decades, increasing concerns regarding fossil fuel depletion and
excessive CO2 emissions have led to extensive fundamental studies and industrial trials …

Production of polymalic acid and malic acid by Aureobasidium pullulans fermentation and acid hydrolysis

X Zou, Y Zhou, ST Yang - Biotechnology and bioengineering, 2013 - Wiley Online Library
Malic acid is a dicarboxylic acid widely used in the food industry and also a potential C4
platform chemical that can be produced from biomass. However, microbial fermentation for …

Current advance in biological production of malic acid using wild type and metabolic engineered strains

Z Dai, H Zhou, S Zhang, H Gu, Q Yang, W Zhang… - Bioresource …, 2018 - Elsevier
Abstract Malic acid (2-hydroxybutanedioic acid) is a four-carbon dicarboxylic acid, which has
attracted great interest due to its wide usage as a precursor of many industrially important …

Biosynthesis of polymalic acid in fermentation: advances and prospects for industrial application

X Zou, C Cheng, J Feng, X Song, M Lin… - Critical reviews in …, 2019 - Taylor & Francis
Some microorganisms naturally produce β-poly (l-malic acid)(PMA), which has excellent
water solubility, biodegradability, and biocompatibility properties. PMA has broad …

Microbial biosynthesis and secretion of l-malic acid and its applications

Z Chi, ZP Wang, GY Wang, I Khan… - Critical reviews in …, 2016 - Taylor & Francis
Abstract l-Malic acid has many uses in food, beverage, pharmaceutical, chemical and
medical industries. It can be produced by one-step fermentation, enzymatic transformation of …

Highly efficient neutralizer-free l-malic acid production using engineered Saccharomyces cerevisiae

L Sun, Q Zhang, X Kong, Y Liu, J Li, G Du, X Lv… - Bioresource …, 2023 - Elsevier
In industrial bioproduction of organic acids, numerous neutralizers are required which
substantially increases production costs and burdens the environment. To address this …

Engineering rTCA pathway and C4-dicarboxylate transporter for l-malic acid production

X Chen, Y Wang, X Dong, G Hu, L Liu - Applied Microbiology and …, 2017 - Springer
Abstract l-Malic acid is an important component of a vast array of food additives,
antioxidants, disincrustants, pharmaceuticals, and cosmetics. Here, we presented a pathway …

A review on the lactic acid fermentation from low-cost renewable materials: Recent developments and challenges

A Ahmad, F Banat, H Taher - Environmental Technology & Innovation, 2020 - Elsevier
Recently, lactic acid production from renewable materials has gained enormous attention
due to the several functional properties it offers in different fields. The high yield productivity …