[HTML][HTML] Fatty acid-binding proteins 3 and 5 are involved in the initiation of mitochondrial damage in ischemic neurons

Q Guo, I Kawahata, A Cheng, H Wang, W Jia… - Redox Biology, 2023 - Elsevier
We have previously shown that a fatty acid-binding protein7 (FABP7) inhibitor ameliorates
cerebral ischemia-reperfusion injury in mice, suggesting an association between FABPs and …

Fatty acid-binding proteins aggravate cerebral ischemia-reperfusion injury in mice

Q Guo, I Kawahata, T Degawa, Y Ikeda-Matsuo, M Sun… - Biomedicines, 2021 - mdpi.com
Fatty acid-binding proteins (FABPs) regulate the intracellular dynamics of fatty acids,
mediate lipid metabolism and participate in signaling processes. However, the therapeutic …

Roles of fatty acid binding protein 7 in ischemic neuronal injury and ischemia-induced neurogenesis after transient forebrain ischemia

T Kato, H Yoshioka, Y Owada, H Kinouchi - Brain Research, 2020 - Elsevier
Fatty acid binding protein 7 (FABP7) has a protective role in the central nervous system
injury and regulates neurogenesis during brain development; however, its roles in neuronal …

FABP7 upregulation induces a neurotoxic phenotype in astrocytes

KM Killoy, BA Harlan, M Pehar, MR Vargas - Glia, 2020 - Wiley Online Library
Fatty acid binding proteins (FABPs) are key regulators of lipid metabolism, energy
homeostasis, and inflammation. They participate in fatty acid metabolism by regulating their …

FABP7 protects astrocytes against ROS toxicity via lipid droplet formation

A Islam, Y Kagawa, H Miyazaki, SK Shil… - Molecular …, 2019 - Springer
Fatty acid-binding proteins (FABPs) bind and internalize long-chain fatty acids, controlling
lipid dynamics. Recent studies have proposed the involvement of FABPs, particularly …

FABP7 expression in normal and stab-injured brain cortex and its role in astrocyte proliferation

K Sharifi, Y Morihiro, M Maekawa, Y Yasumoto… - Histochemistry and cell …, 2011 - Springer
Reactive gliosis, in which astrocytes as well as other types of glial cells undergo massive
proliferation, is a common hallmark of all brain pathologies. Brain-type fatty acid-binding …

Fatty acid-binding protein 3 contributes to ischemic heart injury by regulating cardiac myocyte apoptosis and MAPK pathways

L Zhuang, C Li, Q Chen, Q Jin, L Wu… - American Journal …, 2019 - journals.physiology.org
Fatty acid-binding protein 3 (FABP3), a low-molecular-weight protein, participates in lipid
transportation, storage, signaling transduction, oxidation, and transcription regulation. Here …

A novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse models

A Cheng, W Jia, I Kawahata, K Fukunaga - EBioMedicine, 2021 - thelancet.com
Background Multiple sclerosis (MS) is an autoimmune disease characterised by the
demyelination of mature oligodendrocytes in the central nervous system. Recently, several …

A Dichotomous role for FABP7 in sleep and Alzheimer's disease pathogenesis: a hypothesis

H Needham, G Torpey, CC Flores, CJ Davis… - Frontiers in …, 2022 - frontiersin.org
Fatty acid binding proteins (FABPs) are a family of intracellular lipid chaperone proteins
known to play critical roles in the regulation of fatty acid uptake and transport as well as …

FABP4 alleviates endoplasmic reticulum stress‑mediated ischemia‑reperfusion injury in PC12 cells via regulation of PPARγ

XL Yang, JH Mi, Q Dong - … and Therapeutic Medicine, 2021 - spandidos-publications.com
Ischemic stroke is a life‑threatening complication with a high rate of morbidity. Circulating
fatty acid binding protein 4 (FABP4) has been reported to be associated with the outcome of …