Runt‑related transcription factor (RUNX) proteins belong to a transcription factors family
known as master regulators of important embryonic developmental programs. In the last …

The Runt‐related transcription factors (RUNX) belong to an ancient family of metazoan
genes involved in developmental processes. Through multiple protein‐interacting partners …

OBJECTIVE: The Runt domain transcription factor, RUNX3, has been shown to be a tumor
suppressor in a variety of cancers including gastric, colon and breast cancer. Interestingly …

Cumulative evidences show that Runt‐related transcription factor 3 (RUNX3) has a tumor
suppressive role in various cancers. In particular, RUNX3 appears to be an important …

Background Runt-related transcription factor 1 (RUNX1) is a heterodimeric transcription
factor that binds to the core element of many enhancers and promoters and can accelerate …

Runt-related transcription factor 1 (RUNX1) is frequently involved in the progression of acute
leukemia. However, emerging and discoverable RUNX1 somatic mutations, RUNX1 …

RUNX proteins belong to a family of metazoan transcription factors that serve as master
regulators of development. They are frequently deregulated in human cancers, indicating a …

The runt-related transcription factors (RUNX) play prominent roles in cell cycle progression,
differentiation, apoptosis, immunity and epithelial–mesenchymal transition. There are three …

Despite advances in early diagnosis and treatment, cancer remains the major reason for
mortality worldwide. The Runt-related transcription factor (RUNX) family has been reported …

Runt-related transcriptional factor gene 3 (RUNX3) belongs to the runt domain family of
transcriptional factors that plays an important role during normal tissue development and in …