[HTML][HTML] From belly to brain: targeting the ghrelin receptor in appetite and food intake regulation
Ghrelin is the only known peripherally-derived orexigenic hormone, increasing appetite and
subsequent food intake. The ghrelinergic system has therefore received considerable …
subsequent food intake. The ghrelinergic system has therefore received considerable …
Lean mean fat reducing “ghrelin” machine: hypothalamic ghrelin and ghrelin receptors as therapeutic targets in obesity
Obesity has reached epidemic proportions not only in Western societies but also in the
developing world. Current pharmacological treatments for obesity are either lacking in …
developing world. Current pharmacological treatments for obesity are either lacking in …
[HTML][HTML] Therapeutic potential of targeting the ghrelin pathway
Ghrelin was discovered in 1999 as the endogenous ligand of the growth-hormone
secretagogue receptor 1a (GHSR1a). Since then, ghrelin has been found to exert a plethora …
secretagogue receptor 1a (GHSR1a). Since then, ghrelin has been found to exert a plethora …
Targeting the ghrelin receptor to regulate food intake
I Depoortere - Regulatory peptides, 2009 - Elsevier
The increasing prevalence of obesity and the obesity-associated morbidities represent one
of the major health problems of the western society. This has renewed interest in our …
of the major health problems of the western society. This has renewed interest in our …
Ghrelin in the regulation of body weight and metabolism
TR Castaneda, J Tong, R Datta, M Culler… - Frontiers in …, 2010 - Elsevier
Ghrelin, a peptide hormone predominantly produced by the stomach, was isolated as the
endogenous ligand for the growth hormone secretagogue receptor. Ghrelin is a potent …
endogenous ligand for the growth hormone secretagogue receptor. Ghrelin is a potent …
Current understanding of the hypothalamic ghrelin pathways inducing appetite and adiposity
Ghrelin is a multifaceted regulator of metabolism. Ghrelin regulates energy balance in the
short term via induction of appetite and in the long term via increased body weight and …
short term via induction of appetite and in the long term via increased body weight and …
[HTML][HTML] Clarifying the ghrelin system's ability to regulate feeding behaviours despite enigmatic spatial separation of the GHSR and its endogenous ligand
A Edwards, A Abizaid - International journal of molecular sciences, 2017 - mdpi.com
Ghrelin is a hormone predominantly produced in and secreted from the stomach. Ghrelin is
involved in many physiological processes including feeding, the stress response, and in …
involved in many physiological processes including feeding, the stress response, and in …
[HTML][HTML] Ghrelin and the regulation of food intake and energy balance
H Hosoda, M Kojima… - Molecular …, 2002 - triggered.edina.clockss.org
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is
synthesized principally in the stomach and is released in response to acute and chronic …
synthesized principally in the stomach and is released in response to acute and chronic …
Ghrelin and appetite control in humans—potential application in the treatment of obesity
M Patterson, SR Bloom, JV Gardiner - Peptides, 2011 - Elsevier
Ghrelin is a peptide hormone secreted into circulation from the stomach. It has been
postulated to act as a signal of hunger. Ghrelin administration acutely increases energy …
postulated to act as a signal of hunger. Ghrelin administration acutely increases energy …
The many faces of ghrelin: new perspectives for nutrition research?
B Otto, J Spranger, SC Benoit, DJ Clegg… - The British Journal of …, 2005 - europepmc.org
The appetite-modulating peptide ghrelin is predominantly produced and secreted by the
stomach and shows a strong growth hormone-releasing activity, which is mediated by the …
stomach and shows a strong growth hormone-releasing activity, which is mediated by the …