The rapid rise in atopy and asthma in industrialized nations has led to the identification of
early life environmental factors that promote these conditions and spurred research into how …

Asthma is a chronic inflammatory immune disorder of the airways affecting one in ten
children in westernized countries. The geographical disparity combined with a generational …

The human microbiota has been established as a key regulator of host health, in large part
owing to its constant interaction with and impact on host immunity. A range of environmental …

This review presents a comprehensive examination of the various factors contributing to the
immunopathogenesis of asthma from the prenatal to preschool period. We focus on …

The non‐communicable disease pandemic includes immune‐mediated diseases such as
asthma and allergy, which are likely originating in early life where the immature immune …

Asthma is the most prevalent non-communicable disease in childhood, characterized by
reversible airway constriction and inflammation of the lower airways. The respiratory tract …

During and immediately after birth, neonates are exposed to an environment laden with
bacteria, a stark contrast to the sterile environment of the womb. Over the ensuing weeks …

Asthma is a chronic and heterogeneous respiratory disease with many risk factors that
typically originate during early childhood. A complex interplay between environmental …

Early life dietary patterns and timely maturation of mucosa‐associated microbial
communities are important factors influencing immune development and for establishing …

Atopy and asthma appear to have their roots in an insufficiency of early-life exposure to the
diverse environmental microbiota necessary to ensure colonization of the gastrointestinal …