Objectives Small animal maxillofacial models, such as non-segmental critical size defects
(CSDs) in the rabbit mandible, need to be standardized for use as preclinical models of …

Abstract (J Korean Assoc Oral Maxillofac Surg 2016; 42: 20-30) Objectives: To validate a
critical-size mandibular bone defect model in miniature pigs. Materials and Methods …

Objective To evaluate a rabbit model of mandibular box-shaped defects created through an
intraoral approach and determine the minimum size defect that would not spontaneously …

Purpose: The goal of this study was to identify bone defects of critical size in C57BL/6 mouse
mandibles. Materials and Methods: Twenty-four male mice were included in this study. All …

Importance Advances in tissue engineering offer potential alternatives to current mandibular
reconstructive techniques; however, before clinical translation of this technology, a relevant …

Goal Evaluate bone regeneration in a critical size bone defect model in the jaw of healthy
rats as a function of gender and defect location. Design A series of microCT and histological …

Purpose A large animal model is desired for preclinical studies aimed at reconstructing
severe mandibular skeletal defects using tissue engineering techniques. To identify the size …

Objectives: To perform a systematic literature review of studies involving critical size defects
(CSDs) in the dog mandible and calvarium to find out the common characteristics of CSDs …

Objectives Minipigs present advantages for studying oral bone regeneration; however,
standardized critical size defects (CSD) for alveolar bone have not been validated yet. The …

Little consistency has been manifest among investigators in choosing an appropriate
experimental model for maxillofacial bone research. In an effort to develop a protocol for the …