The classification and monitoring of individuals with early knee osteoarthritis (OA) are
important considerations for the design and evaluation of therapeutic interventions and …

Objective To propose draft classification criteria for early stage osteoarthritis (OA) of the knee
for use in a primary care setting. Methods A group of basic scientists, physician-scientists …

Osteoarthritis (OA) remains the most challenging arthritic disorder, with a high burden of
disease and no available disease-modifying treatments. Symptomatic early-stage OA of the …

Objective To facilitate a greater likelihood of favorable response to new disease-modifying
therapies, recruitment of patients at an earlier stage of their disease into clinical trials may be …

Introduction We performed a systematic review of prognostic factors for the progression of
symptomatic knee osteoarthritis (OA), defined as increase in pain, decline in physical …

Objective To systematically summarize the literature on the course of pain in patients with
knee osteoarthritis (OA), prognostic factors that predict deterioration of pain, the course of …

Objective To identify, by systematic review, patient characteristics that can be used by health
care practitioners to predict the likelihood of knee osteoarthritis (OA) progression. Methods A …

There is an increasing awareness on the importance in identifying early phases of the
degenerative processes in knee osteoarthritis (OA), the crucial period of the disease when …

Background Large variations in pain and function are seen over time in subjects at risk for
and with radiographic knee osteoarthritis (OA). We hypothesized that this variation may be …

Background GPs have high consultation rates for symptoms related to knee osteoarthritis
(OA). Many risk factors for symptomatic knee OA progression remain unknown. Aim To …