Background: Platelets can infiltrate ischemic myocardium and are increasingly recognized
as critical regulators of inflammatory processes during myocardial ischemia and reperfusion …

Previous studies have suggested that microRNAs (miRNAs) are associated with the
progression of myocardial ischemic reperfusion (I/R) injury. However, inconsistent results …

MicroRNAs (miRNAs) are a class of small single-stranded and highly conserved non-coding
RNAs, which are closely linked to cardiac disorders such as myocardial infarction (MI) …

Myocardial ischaemia/reperfusion (I/R)-induced remodelling generally includes cell death
(necrosis and apoptosis), myocyte hypertrophy, angiogenesis, cardiac fibrosis, and …

After an ischemic injury, the heart undergoes a complex process of structural and functional
remodeling that involves several steps, including inflammatory and fibrotic responses. In this …

MicroRNAs (miRNAs) are small (∼ 22 nt) noncoding single-stranded RNA molecules that
downregulate gene expression. Studies have shown that miRNAs control diverse aspects of …

Cardiovascular disease—a leading cause of morbidity and mortality among adults—is
strongly influenced by platelet function through acute thrombotic and atherogenic …

Highlights•Ischemic heart disease is a leading cause of morbidity and mortality.•MicroRNAs
regulate gene expression by translational inhibition and degradation of target …

Platelets play a crucial role in the pathogenesis of myocardial infarction (MI) by adhering to
the site of a ruptured atherosclerotic plaque. The aim of this study was to screen for …

Rationale Myocardial infarction (MI) triggers a dynamic microRNA response with the
potential of yielding therapeutic targets. Objective We aimed to identify novel aberrantly …