[HTML][HTML] Integrated phosphoproteome and transcriptome analysis reveals chlamydia-induced epithelial-to-mesenchymal transition in host cells
Chlamydia trachomatis (Ctr) causes a range of infectious diseases and is epidemiologically
associated with cervical and ovarian cancers. To obtain a panoramic view of Ctr-induced …
associated with cervical and ovarian cancers. To obtain a panoramic view of Ctr-induced …
[HTML][HTML] Role of Epithelial-Mesenchyme Transition in Chlamydia Pathogenesis
JU Igietseme, Y Omosun, O Stuchlik, MS Reed… - PloS one, 2015 - journals.plos.org
Chlamydia trachomatis genital infection in women causes serious adverse reproductive
complications, and is a strong co-factor for human papilloma virus (HPV)-associated cervical …
complications, and is a strong co-factor for human papilloma virus (HPV)-associated cervical …
[HTML][HTML] The role of infected epithelial cells in Chlamydia-associated fibrosis
LT Caven, RA Carabeo - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Ocular, genital, and anogenital infection by the obligate intracellular pathogen Chlamydia
trachomatis have been consistently associated with scar-forming sequelae. In cases of …
trachomatis have been consistently associated with scar-forming sequelae. In cases of …
A Loss-of-Function Screen Reveals Ras- and Raf-Independent MEK-ERK Signaling During Chlamydia trachomatis Infection
RK Gurumurthy, AP Mäurer, N Machuy, S Hess… - Science …, 2010 - science.org
Chlamydiae are obligate intracellular bacterial pathogens that have a major effect on human
health. Because of their intimate association with their host, chlamydiae depend on various …
health. Because of their intimate association with their host, chlamydiae depend on various …
Epidermal Growth Factor Receptor and Transforming Growth Factor β Signaling Pathways Cooperate To Mediate Chlamydia Pathogenesis
Human genital Chlamydia infection is a major public health concern due to the serious
reproductive system complications. Chlamydia binds several receptor tyrosine kinases …
reproductive system complications. Chlamydia binds several receptor tyrosine kinases …
[HTML][HTML] Early Transcriptional Landscapes of Chlamydia trachomatis-Infected Epithelial Cells at Single Cell Resolution
RJ Hayward, JW Marsh, MS Humphrys… - Frontiers in cellular …, 2019 - frontiersin.org
Chlamydia are Gram-negative obligate intracellular bacterial pathogens responsible for a
variety of disease in humans and animals worldwide. Chlamydia trachomatis causes …
variety of disease in humans and animals worldwide. Chlamydia trachomatis causes …
[HTML][HTML] Chlamydia infection promotes host DNA damage and proliferation but impairs the DNA damage response
The obligate intracellular bacterial pathogen Chlamydia trachomatis (Ctr) has been
associated with cervical and ovarian cancer development. However, establishment of …
associated with cervical and ovarian cancer development. However, establishment of …
Molecular pathogenesis of chlamydia disease complications: epithelial-mesenchymal transition and fibrosis
JU Igietseme, Y Omosun, T Nagy, O Stuchlik… - Infection and …, 2018 - Am Soc Microbiol
The reproductive system complications of genital chlamydial infection include fallopian tube
fibrosis and tubal factor infertility. However, the molecular pathogenesis of these …
fibrosis and tubal factor infertility. However, the molecular pathogenesis of these …
[HTML][HTML] The impact of protein phosphorylation on chlamydial physiology
JE Claywell, LM Matschke, DJ Fisher - Frontiers in cellular and …, 2016 - frontiersin.org
Chlamydia are Gram negative bacterial pathogens responsible for disease in humans and
economically important domesticated animals. As obligate intracellular bacteria, they must …
economically important domesticated animals. As obligate intracellular bacteria, they must …
[HTML][HTML] Chlamydia trachomatis-induced alterations in the host cell proteome are required for intracellular growth
Intracellular pathogens directly alter host cells in order to replicate and survive. While
infection-induced changes in host transcription can be readily assessed, posttranscriptional …
infection-induced changes in host transcription can be readily assessed, posttranscriptional …