Cardiovascular disease (CVD) is the leading cause of death worldwide, and extensive
research has been performed to understand this disease better, using various experimental …

Endothelial cells play a key role in prominent immunological and pathological processes
such as leukocyte trafficking, inflammation, atheroma or cancer cell metastasis. Umbilical …

Human umbilical vein endothelial cells (HUVECs) cultured in vitro are a commonly used
experimental system. When properly differentiated they acquire the so-called cobblestone …

Angiogenesis is a complex multi-step process, where in response to angiogenic stimuli, new
vessels are created from the existing vasculature. These steps include: degradation of the …

Background Human umbilical endothelial cells (HUVECs) are widely used to study the
endothelial physiology and pathology that might be involved in sex and gender differences …

We describe a protocol for easy isolation and culture of human umbilical vein endothelial
cells (HUVECs) to supply every researcher with a method that can be applied in cell biology …

To gain insight into the role of the endothelial cell during the pathophysiology of the
angiogenic response, investigators have isolated micro-and macrovascular endothelial cells …

Heart valves are solely responsible for maintaining unidirectional blood flow through the
cardiovascular system. These thin, fibrous tissues are subjected to significant mechanical …

Objective: Endothelial progenitor cells (EPC) can contribute to vascular repair and targeted
tumour therapy. Little is known about generating EPC from human umbilical cord blood. We …

The vascular endothelial cell (EC) plays an essential role in the pathogenesis of
inflammation, transplant rejection and tumour metastasis. Most research on vascular ECs …