Autophagy is a highly conserved lysosomal degradation pathway active at basal levels in all
cells. However, under stress conditions, such as a lack of nutrients or trophic factors, it works …

(Macro) autophagy is a bulk degradation process that mediates the clearance of long-lived
proteins and organelles. Autophagy is initiated by double-membraned structures, which …

Autophagy is a highly conserved catabolic process induced under various conditions of
cellular stress, which prevents cell damage and promotes survival in the event of energy or …

Significance: Autophagy is a highly conserved eukaryotic cellular recycling process.
Through the degradation of cytoplasmic organelles, proteins, and macromolecules, and the …

The degradation of intracellular components in lysosomes (autophagy) has recaptured the
attention of cell biologists in recent years. The main reason for this renewed interest is the …

Autophagy is a lysosome-dependent cellular degradation program that responds to a variety
of environmental and cellular stresses. It is an evolutionarily well-conserved and essential …

Autophagy is a lysosomal degradation pathway that is essential for survival, differentiation,
development, and homeostasis. Autophagy principally serves an adaptive role to protect …

Autophagy is a degradative mechanism mainly involved in the recycling and turnover of
cytoplasmic constituents from eukaryotic cells. Over the last years, yeast genetic screens …

Autophagy is a catabolic trafficking pathway for bulk destruction and turnover of long-lived
proteins and organelles via regulated lysosomal degradation. In eukaryotic cells, autophagy …

Autophagy is a conserved catabolic process that delivers the cytosol and cytosolic
constituents to the lysosome. Its fundamental role is to maintain cellular homeostasis and to …