[HTML][HTML] Gut-derived metabolites and their role in immune dysfunction in chronic kidney disease
G Glorieux, T Gryp, A Perna - Toxins, 2020 - mdpi.com
Several of the uremic toxins, which are difficult to remove by dialysis, originate from the gut
bacterial metabolism. This opens opportunities for novel targets trying to decrease …
bacterial metabolism. This opens opportunities for novel targets trying to decrease …
[HTML][HTML] Gut microbiota generation of protein-bound uremic toxins and related metabolites is not altered at different stages of chronic kidney disease
T Gryp, K De Paepe, R Vanholder, FM Kerckhof… - Kidney international, 2020 - Elsevier
Chronic kidney disease (CKD) is characterized by accumulation of protein-bound uremic
toxins such as p-cresyl sulfate, p-cresyl glucuronide, indoxyl sulfate and indole-3-acetic acid …
toxins such as p-cresyl sulfate, p-cresyl glucuronide, indoxyl sulfate and indole-3-acetic acid …
Protein-bound uremic toxins and immunity
Protein-bound uremic toxins (PBUTs) are bioactive microbiota metabolites originated
exclusively from protein fermentation of the bacterial community resident within the gut …
exclusively from protein fermentation of the bacterial community resident within the gut …
[HTML][HTML] The impact of CKD on uremic toxins and gut microbiota
J Rysz, B Franczyk, J Ławiński, R Olszewski… - Toxins, 2021 - mdpi.com
Numerous studies have indicated that the progression of chronic kidney disease (CKD) to
end-stage renal disease (ESRD) is strictly associated with the accumulation of toxic …
end-stage renal disease (ESRD) is strictly associated with the accumulation of toxic …
[HTML][HTML] Homeostasis in the gut microbiota in chronic kidney disease
The gut microbiota consists of trillions of microorganisms, fulfilling important roles in
metabolism, nutritional intake, physiology and maturation of the immune system, but also …
metabolism, nutritional intake, physiology and maturation of the immune system, but also …
[HTML][HTML] Chronic kidney disease-associated immune dysfunctions: impact of protein-bound uremic retention solutes on immune cells
Regardless of the primary disease responsible for kidney failure, patients suffering from
chronic kidney disease (CKD) have in common multiple impairments of both the innate and …
chronic kidney disease (CKD) have in common multiple impairments of both the innate and …
[HTML][HTML] From the gastrointestinal tract (GIT) to the kidneys: live bacterial cultures (probiotics) mediating reductions of uremic toxin levels via free radical signaling
L Vitetta, AW Linnane, GC Gobe - Toxins, 2013 - mdpi.com
A host of compounds are retained in the body of uremic patients, as a consequence of
progressive renal failure. Hundreds of compounds have been reported to be retention …
progressive renal failure. Hundreds of compounds have been reported to be retention …
Gut microbiome in chronic kidney disease
MR Wing, SS Patel, A Ramezani… - Experimental …, 2016 - Wiley Online Library
New Findings What is the topic of this review? This review addresses the contribution of the
altered gut microbiome to uraemic syndrome, with specific reference to gut microbiome …
altered gut microbiome to uraemic syndrome, with specific reference to gut microbiome …
[HTML][HTML] Biotics (Pre-, pro-, post-) and uremic toxicity: implications, mechanisms, and possible therapies
In recent years, more scientific data have pointed out the close connection between
intestinal microbial community, nutritional habits, lifestyle, and the appearance of various …
intestinal microbial community, nutritional habits, lifestyle, and the appearance of various …
[HTML][HTML] Microbial-derived tryptophan catabolites, kidney disease and gut inflammation
AM Madella, J Van Bergenhenegouwen, J Garssen… - Toxins, 2022 - mdpi.com
Uremic metabolites, molecules either produced by the host or from the microbiota population
existing in the gastrointestinal tract that gets excreted by the kidneys into urine, have …
existing in the gastrointestinal tract that gets excreted by the kidneys into urine, have …