A role for agouti-related protein in appetite regulation in a species with continuous nutrient delivery

CG Wagner, CD McMahon, DL Marks, JA Daniel… - …, 2005 - karger.com
Abstract Knowledge of specific neurotransmitters as well as the pathways and mechanisms
regulating appetite in ruminants that continually graze, such as sheep, is incomplete …

Altered expression of agouti-related protein and its colocalization with neuropeptide Y in the arcuate nucleus of the hypothalamus during lactation

P Chen, C Li, C Haskell-Luevano, RD Cone… - …, 1999 - academic.oup.com
During lactation, the levels of neuropeptide Y (NPY), which plays an important role in
mediating food intake, are significantly elevated in a number of hypothalamic areas …

Effects of Agouti‐Related Protein on Metabolism and Hypothalamic Neuropeptide Gene Expression

J Korner, S Wissig, A Kim, IM Conwell… - Journal of …, 2003 - Wiley Online Library
The hypothalamic melanocortin system regulates feeding in part through interaction of the
appetite stimulating peptide, agouti‐related protein (AGRP), and the anorectic peptide, α …

Hypothalamic agouti‐related protein expression is affected by both acute and chronic experience of food restriction and re‐feeding in chickens

IC Dunn, PW Wilson, TV Smulders… - Journal of …, 2013 - Wiley Online Library
The central melanocortin system is conserved across vertebrates. However, in birds, little is
known about how energy balance influences orexigenic agouti‐related protein (AGRP) and …

Mechanisms for AgRP neuron-mediated regulation of appetitive behaviors in rodents

MA Thomas, B Xue - Physiology & behavior, 2018 - Elsevier
The obesity epidemic is a major health and economic burden facing both developed and
developing countries worldwide. Interrogation of the central and peripheral mechanisms …

Hypothalamic agouti‐related peptide mRNA is elevated during natural and stress‐induced anorexia

IC Dunn, PW Wilson, RB D'Eath… - Journal of …, 2015 - Wiley Online Library
As part of their natural lives, animals can undergo periods of voluntarily reduced food intake
and body weight (ie animal anorexias) that are beneficial for survival or breeding, such as …

Neurochemical phenotype of hypothalamic neurons showing Fos expression 23 h after intracranial AgRP

H Zheng, MM Corkern, SM Crousillac… - American Journal …, 2002 - journals.physiology.org
Agouti-related protein (AgRP) is coexpressed with neuropeptide Y (NPY) in a population of
neurons in the arcuate nucleus (ARC) of the hypothalamus and stimulates food intake for up …

Effects of chronic central nervous system administration of agouti-related protein in pair-fed animals

CJ Small, MS Kim, SA Stanley, JRD Mitchell… - Diabetes, 2001 - Am Diabetes Assoc
The melanocortin receptor (MC3-R and MC4-R) antagonist, agouti-related protein (AGRP),
is a potent stimulant of food intake. We examined the effect of chronic intracerebroventricular …

Agouti-related protein (AGRP) has a central inhibitory action on the hypothalamic-pituitary-thyroid (HPT) axis; comparisons between the effect of AGRP and …

C Fekete, S Sarkar, WM Rand, JW Harney… - …, 2002 - academic.oup.com
Because α-MSH has a potent stimulatory action on hypophysiotropic TRH synthesizing
neurons in the hypothalamic paraventricular nucleus (PVN), preventing the effects of fasting …

Role of agouti-related protein-expressing neurons in lactation

CT Phillips, RD Palmiter - Endocrinology, 2008 - academic.oup.com
Hypothalamic neurons that express agouti-related protein (AgRP) and neuropeptide Y
(NPY) are thought to be important for regulation of feeding, especially under conditions of …