Hydrogenases are nature's catalysts designed to extract protons from molecular hydrogen
(H2) thereby forming a reactive hydride species (H−). Those enzymes capable of catalyzing …

Hydrogenases represent a heterogeneous group of enzymes consisting of three
evolutionary unrelated classes, ie [NiFe],[FeFe] and [Fe] hydrogenases. They allow the uni …

Hydrogenases, abundant proteins in the microbial world, catalyze cleavage of H 2 into
protons and electrons or the evolution of H 2 by proton reduction. Hydrogen metabolism …

Abstract [FeFe]-hydrogenases catalyse H 2 production at exceptionally high turnover
numbers (up to 10 4 s− 1). They are found in a variety of strict or facultative anaerobic …

Hydrogenases are efficient biological catalysts of H2 oxidation and production. Most of them
are inhibited by O2, and a prerequisite for their use in biotechnological applications under …

Abstract Dioxygen-tolerant [NiFe]-hydrogenases are defined by their ability to catalyze the
reaction, H 2⇌ 2H++ 2e− even in the presence of O 2. Catalytic and probably also …

Recent research on hydrogenases has been notably motivated by a desire to utilize these
remarkable hydrogen oxidation catalysts in biotechnological applications. Progress in the …

The [NiFe]-and [FeFe]-hydrogenases have convergently evolved to efficiently catalyze the
reversible oxidation of molecular H2. Extensive research efforts are currently aimed at using …

Biocatalysts that mediate the H 2-dependent reduction of NAD+ to NADH are attractive from
both a fundamental and applied perspective. Here we present the first biochemical and …

Many microorganisms, such as methanogenic, acetogenic, nitrogen-fixing, photosynthetic,
or sulfate-reducing bacteria, metabolize hydrogen.[1, 2a] Hydrogen activation is mediated by …