Accurate pan-specific prediction of peptide-MHC class II binding affinity with improved binding core identification
M Andreatta, E Karosiene, M Rasmussen, A Stryhn… - Immunogenetics, 2015 - Springer
A key event in the generation of a cellular response against malicious organisms through
the endocytic pathway is binding of peptidic antigens by major histocompatibility complex …
the endocytic pathway is binding of peptidic antigens by major histocompatibility complex …
NetMHCpan-4.1 and NetMHCIIpan-4.0: improved predictions of MHC antigen presentation by concurrent motif deconvolution and integration of MS MHC eluted ligand …
Major histocompatibility complex (MHC) molecules are expressed on the cell surface, where
they present peptides to T cells, which gives them a key role in the development of T-cell …
they present peptides to T cells, which gives them a key role in the development of T-cell …
NetMHCcons: a consensus method for the major histocompatibility complex class I predictions
A key role in cell-mediated immunity is dedicated to the major histocompatibility complex
(MHC) molecules that bind peptides for presentation on the cell surface. Several in silico …
(MHC) molecules that bind peptides for presentation on the cell surface. Several in silico …
NetMHCIIpan-3.0, a common pan-specific MHC class II prediction method including all three human MHC class II isotypes, HLA-DR, HLA-DP and HLA-DQ
Major histocompatibility complex class II (MHCII) molecules play an important role in cell-
mediated immunity. They present specific peptides derived from endosomal proteins for …
mediated immunity. They present specific peptides derived from endosomal proteins for …
NetMHCpan-4.0: improved peptide–MHC class I interaction predictions integrating eluted ligand and peptide binding affinity data
Cytotoxic T cells are of central importance in the immune system's response to disease.
They recognize defective cells by binding to peptides presented on the cell surface by MHC …
They recognize defective cells by binding to peptides presented on the cell surface by MHC …
MHC class II epitope predictive algorithms
Major histocompatibility complex class II (MHC‐II) molecules sample peptides from the
extracellular space, allowing the immune system to detect the presence of foreign microbes …
extracellular space, allowing the immune system to detect the presence of foreign microbes …
Improved methods for predicting peptide binding affinity to MHC class II molecules
Major histocompatibility complex class II (MHC‐II) molecules are expressed on the surface
of professional antigen‐presenting cells where they display peptides to T helper cells, which …
of professional antigen‐presenting cells where they display peptides to T helper cells, which …
Pan-specific MHC class I predictors: a benchmark of HLA class I pan-specific prediction methods
H Zhang, C Lundegaard, M Nielsen - Bioinformatics, 2009 - academic.oup.com
Motivation: MHC: peptide binding plays a central role in activating the immune surveillance.
Computational approaches to determine T-cell epitopes restricted to any given major …
Computational approaches to determine T-cell epitopes restricted to any given major …
Toward more accurate pan-specific MHC-peptide binding prediction: a review of current methods and tools
L Zhang, K Udaka, H Mamitsuka… - Briefings in …, 2012 - academic.oup.com
Binding of short antigenic peptides to major histocompatibility complex (MHC) molecules is
a core step in adaptive immune response. Precise identification of MHC-restricted peptides …
a core step in adaptive immune response. Precise identification of MHC-restricted peptides …
[HTML][HTML] NetMHCIIpan-2.0 - Improved pan-specific HLA-DR predictions using a novel concurrent alignment and weight optimization training procedure
Background Binding of peptides to Major Histocompatibility class II (MHC-II) molecules play
a central role in governing responses of the adaptive immune system. MHC-II molecules …
a central role in governing responses of the adaptive immune system. MHC-II molecules …