The neuroendocrine tumours pheochromocytomas and paragangliomas carry the highest
degree of heritability in human neoplasms, enabling genetic alterations to be traced to …

Pheochromocytomas (PCCs) and paragangliomas (PGLs) are catecholamine-secreting
tumors of neural crest origin. Once collectively known as the '10% tumor', based on the …

Paragangliomas and phaeochromocytomas are neuroendocrine tumours whose
pathogenesis and progression are very strongly influenced by genetics. A germline mutation …

A molecular biology–based taxonomy has been proposed for pheochromocytoma and
paraganglioma (PPGL). Data from the Cancer Genome Atlas revealed clinically relevant …

Malignant pheochromocytomas and paragangliomas affect a very small percentage of the
general population. A substantial number of these patients have a hereditary predisposition …

The genetics of pheochromocytoma and paraganglioma (PPGL) has become increasingly
complex over the last two decades. The list of genes involved in the development of these …

Pheochromocytomas/paragangliomas are characterized by a unique molecular landscape
that allows their assignment to clusters based on underlying genetic alterations. With around …

Simple Summary Pheochromocytoma and paraganglioma (together PPGL) are rare
neuroendocrine tumors that arise from chromaffin tissue and produce catecholamines …

Recent comprehensive molecular analysis allowed the identification of unique molecular
signatures in pheochromocytomas (PHEOs) and paragangliomas (PGLs). Here we …

Neuroendocrine tumors arising from the adrenal medulla and extra-adrenal ganglia are
called pheochromocytomas and paragangliomas (PCCs/PGLs), respectively. PCCs/PGLs …