Prospective evaluation of the achievement of mucosal healing with anti-TNF-α therapy in a paediatric Crohn's disease cohort
F Nuti, F Civitelli, S Bloise, S Oliva, M Aloi… - Journal of Crohn's …, 2016 - academic.oup.com
Abstract Background and Aims: There is growing evidence that in Crohn's disease the
achievement and maintenance of mucosal healing (MH) through anti-TNFα antibodies may …
achievement and maintenance of mucosal healing (MH) through anti-TNFα antibodies may …
Mucosal healing in pediatric Crohn's disease after anti-TNF therapy: a long-term experience at a single center
Purpose The anti-tumor necrosis factor (TNF) agents infliximab (IFX) and adalimumab (ADA)
have been recently introduced to treat severe inflammatory bowel disease (IBD) that is …
have been recently introduced to treat severe inflammatory bowel disease (IBD) that is …
The impact of infliximab induction therapy on mucosal healing and clinical remission in Polish pediatric patients with moderate-to-severe Crohn's disease
J Kierkus, M Dadalski, E Szymanska… - European journal of …, 2012 - journals.lww.com
Objective To assess the clinical efficacy and the impact of infliximab (IFX) induction therapy
on mucosal healing in Polish children with Crohn's disease (CD). Methods A total of 66 …
on mucosal healing in Polish children with Crohn's disease (CD). Methods A total of 66 …
Predictors of long-term clinical and endoscopic remission in children with Crohn disease treated with infliximab
G D'Arcangelo, S Oliva, A Dilillo, F Viola… - Journal of pediatric …, 2019 - journals.lww.com
Objectives: We aimed to identify early noninvasive predictors of clinical and endoscopic
remission in children with Crohn disease (CD) under infliximab (IFX). Methods: Prospective …
remission in children with Crohn disease (CD) under infliximab (IFX). Methods: Prospective …
Mucosal healing in paediatric patients with moderate-to-severe luminal Crohn's disease under combined immunosuppression: escalation versus early treatment
B Kang, SY Choi, HS Kim, K Kim… - Journal of Crohn's …, 2016 - academic.oup.com
Abstract Background and Aims: We aimed to compare the efficacy of combined
immunosuppression in terms of mucosal healing in paediatric patients with moderate-to …
immunosuppression in terms of mucosal healing in paediatric patients with moderate-to …
Early anti-TNF treatment in pediatric Crohn's disease. Predictors of clinical outcome in a population-based cohort of newly diagnosed patients
C Olbjørn, B Nakstad, MC Småstuen… - Scandinavian journal …, 2014 - Taylor & Francis
Abstract Objective. Pediatric Crohn's disease (CD) is often debilitating, with upper
gastrointestinal (GI) involvement and complications over time. Treatment with tumor necrosis …
gastrointestinal (GI) involvement and complications over time. Treatment with tumor necrosis …
Biological therapy in a pediatric Crohn disease population at a referral center
F Nuti, F Viola, F Civitelli, C Alessandri… - Journal of Pediatric …, 2014 - journals.lww.com
Objective: The antitumor necrosis factor α (TNFα) antibodies infliximab and adalimumab are
effective in inducing and maintaining remission in pediatric patients with Crohn disease …
effective in inducing and maintaining remission in pediatric patients with Crohn disease …
Infliximab trough levels are associated with mucosal healing during maintenance treatment with infliximab in paediatric Crohn's disease
B Kang, SY Choi, YO Choi, SY Lee… - Journal of Crohn's …, 2019 - academic.oup.com
Abstract Background and Aims Mucosal healing is an important treatment goal in Crohn's
disease. We investigated the association between serum infliximab trough levels and …
disease. We investigated the association between serum infliximab trough levels and …
Intestinal healing after anti-TNF induction therapy predicts long-term response to one-year treatment in patients with ileocolonic Crohn's disease naive to anti-TNF …
P Eder, L Łykowska-Szuber, K Katulska… - Gastroenterology …, 2016 - termedia.pl
Aim: To assess the usefulness of intestinal healing phenomenon in CD, defined as
improvement both in endoscopy and MRE, after anti-TNF induction therapy, in predicting …
improvement both in endoscopy and MRE, after anti-TNF induction therapy, in predicting …
[HTML][HTML] Mucosal healing with infliximab: results from the active ulcerative colitis trials
WJ Sandborn - Gastroenterology & hepatology, 2012 - ncbi.nlm.nih.gov
WJS Research has shown that tumor necrosis factor (TNF) is overexpressed in patients with
moderate-tosevere ulcerative colitis (UC); this proinflammatory cytokine can be measured in …
moderate-tosevere ulcerative colitis (UC); this proinflammatory cytokine can be measured in …
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