Adverse effects of titanium dioxide nanoparticles on beneficial gut bacteria and host health based on untargeted metabolomics analysis

Y Wu, X Cao, H Du, X Guo, Y Han… - Environmental …, 2023 - Elsevier
Titanium dioxide (TiO 2) is a common additive in foods, medicines, and personal care
products. In recent years, nano-scale particles in TiO 2 additives have been an increasing …

Effects of oral exposure to titanium dioxide nanoparticles on gut microbiota and gut-associated metabolism in vivo

Z Chen, S Han, D Zhou, S Zhou, G Jia - Nanoscale, 2019 - pubs.rsc.org
The antibacterial activity of titanium dioxide nanoparticles (TiO2 NPs) has been extensively
documented and applied to food packaging or environmental protection. Ingestion of TiO2 …

[HTML][HTML] Intestinal Microecology of Mice Exposed to TiO2 Nanoparticles and Bisphenol A

C Yang, Y Tan, F Li, H Wang, Y Lin, F Lu, H Zhao - Foods, 2022 - mdpi.com
Exposure to titanium dioxide nanoparticles (TiO2 NPs) and bisphenol A (BPA) is ubiquitous,
especially through dietary and other environmental pathways. In the present study, adult …

Titanium dioxide nanoparticles via oral exposure leads to adverse disturbance of gut microecology and locomotor activity in adult mice

S Zhang, X Jiang, S Cheng, J Fan, X Qin, T Wang… - Archives of …, 2020 - Springer
Abstract Titanium dioxide nanoparticles (TiO 2 NPs) have been widely used as food
additives in daily life. However, the impact of oral intake of TiO 2 NPs on the nervous system …

Titanium dioxide nanoparticles elicit lower direct inhibitory effect on human gut microbiota than silver nanoparticles

RT Agans, A Gordon, S Hussain… - Toxicological Sciences, 2019 - academic.oup.com
Due to continued technological development, people increasingly come in contact with
engineered nanomaterials (ENMs) that are now used in foods and many industrial …

Foodborne titanium dioxide nanoparticles induce stronger adverse effects in obese mice than non‐obese mice: gut microbiota dysbiosis, colonic inflammation, and …

X Cao, Y Han, M Gu, H Du, M Song, X Zhu, G Ma… - Small, 2020 - Wiley Online Library
The recent ban of titanium dioxide (TiO2) as a food additive (E171) in France intensified the
controversy on safety of foodborne‐TiO2 nanoparticles (NPs). This study determines the …

Intestinal toxicity of micro-and nano-particles of foodborne titanium dioxide in juvenile mice: Disorders of gut microbiota–host co-metabolites and intestinal barrier …

J Yan, Q Chen, L Tian, K Li, W Lai, L Bian, J Han… - Science of the Total …, 2022 - Elsevier
The wide use of TiO 2 particles in food and the high exposure risk to children have prompted
research into the health risks of TiO 2. We used the microbiome and targeted metabolomics …

Impact of titanium dioxide nanoparticles on intestinal community in 2, 4, 6-trinitrobenzenesulfonic acid (TNBS)-induced acute colitis mice and the intervention effect of …

Y Gao, T Li, S Duan, L Lyu, Y Li, L Xu, Y Wang - Nanoscale, 2021 - pubs.rsc.org
Titanium dioxide nanoparticles (TiO2-NPs) are widely applied as additives in foods due to
their excellent whitening and brightening capability. Although the toxicity and antibacterial …

Effect of long-term intake of dietary titanium dioxide nanoparticles on intestine inflammation in mice

W Mu, Y Wang, C Huang, Y Fu, J Li… - Journal of agricultural …, 2019 - ACS Publications
Early stage exposure of foodborne substances, such as brightening agent titanium dioxide
nanoparticles (TiO2 NPs), can cause long-term effects in adulthood. We aimed to explore …

[HTML][HTML] Dysregulation along the gut microbiota-immune system axis after oral exposure to titanium dioxide nanoparticles: A possible environmental factor promoting …

B Lamas, L Evariste, E Houdeau - Environmental Pollution, 2023 - Elsevier
Food additives are one major hallmark of ultra-processed food in the Western-diet, a food
habit often associated with metabolic disorders. Among these additives, the whitener and …