It has long been observed that heart failure (HF) is associated with measures of systemic
inflammation. In recent years, there have been significant advancements in our …

Chronic inflammation underlies a variety of seemingly unrelated conditions including
coronary artery disease. The interest in exploring the role of inflammation in heart failure …

As a greater proportion of patients survive their initial cardiac insult, medical systems
worldwide are being faced with an ever-growing need to understand the mechanisms …

Inflammation has been recognized as a major pathophysiological contributor to the entire
spectrum of human heart failure (HF), including HF with reduced ejection fraction, HF with …

Inflammation has long been known to play a role in heart failure (HF). Earlier studies
demonstrated that inflammation contributes to the pathogenesis of HF with reduced ejection …

The observation that heart failure with reduced ejection fraction is associated with elevated
circulating levels of pro-inflammatory cytokines opened a new area of research that has …

Despite mounting evidence demonstrating the significance of inflammation in the
pathophysiological mechanisms of heart failure (HF), most large clinical trials that target the …

The increasing prevalence of heart failure poses enormous challenges for health care
systems worldwide. Despite effective medical interventions that target neurohumoral …

Many patients with symptoms and signs of heart failure have a left ventricular ejection
fraction≥ 50%, termed heart failure with preserved ejection fraction (HFpEF). HFpEF is a …

Patients with chronic heart failure (HF) are characterized by systemic inflammation, as
evident by raised circulating levels of several inflammatory cytokines with increasing levels …