Sporadic Alzheimer's disease (SAD) is a slowly progressive neurodegenerative disorder.
This study aimed to investigate neuroprotective potential of tadalafil (TAD) and bergapten …

Background Alzheimer's disease (AD) pathology is associated with complex interactions
among multiple factors, involving an intertwined network of various signaling pathways. The …

Dysregulation of protein homeostasis, proteostasis, is a distinctive hallmark of many
neurodegenerative disorders and aging. Deleteriously, the accumulation of aberrant …

Alzheimer's disease (AD) is portrayed by progressive cognitive decline and pathological
deposition of amyloid plaques as well as neurofibrillary tangles. Most of AD cases are …

Gingerol is a major dietary compound that occurs in several plants belonging to the
Zingiberaceae family. In the current study, the protective effect of gingerol on STZ-induced …

Background Glial activation and neuroinflammation play a crucial role in the pathogenesis
and development of Alzheimer's disease (AD). The receptor for advanced glycation end …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder causing immense
suffering for the patients. Dopamine D2 and 5-hydroxytryptamine receptor 1A (5-HT1A) …

Simple Summary Mangostanaxanthone IV (MX-IV) is a major constituent in Garcinia
mangostana. It induced neuro-protective effects in the ICV-STZ mouse model through …

Alzheimer's disease (AD) is characterized by deposition of amyloid-β (Aβ) plaques,
neurofibrillary tangles, and neuronal loss, accompanied by neuroinflammation …

Embelin, the main active constituent of Embelia ribes, has been reported to possess various
pharmacological actions, including anti-inflammatory, antioxidant, anticonvulsant, and …