The localization of circulating leukocytes within inflamed tissues occurs as the result of
interactions with and migration across vascular endothelium, and is governed, in part, by the …

CD44 on lymphocytes binding to its carbohydrate ligand hyaluronan can mediate primary
adhesion (rolling interactions) of lymphocytes on vascular endothelial cells. This adhesion …

Adhesive interactions between receptors on vascular endothelial cells (EC) and circulating
leukocytes are pivotal in regulating leukocyte extravasation. Although primary adhesion of …

Interactions between complementary receptors on leukocytes and endothelial cells play a
central role in regulating extravasation from the blood and thereby affect both normal and …

CD44 is a widely expressed cell adhesion molecule that has been implicated in a variety of
biological processes including lymphopoiesis, angiogenesis, wound healing, leukocyte …

The present study was undertaken to determine the relationship between the hyaluronate
receptor and CD44 (H-CAM), cell-surface glycoproteins of similar molecular weights that …

Atherosclerosis causes most acute coronary syndromes and strokes. The pathogenesis of
atherosclerosis includes recruitment of inflammatory cells to the vessel wall and activation of …

The extravasation of leukocytes from the blood into tissues occurs as a multistep process: an
initial transient interaction (" rolling"), generally thought to be mediated by the selectin family …

Interactions between CD44 and hyaluronan are implicated in the primary adhesion of
lymphocytes to endothelium at inflammatory locations. Here we show that preincubation of …

Although CD44 is expressed on a wide variety of cell types, few of them use it to recognize
the ligand hyaluronan (HA). A glycosylation-defective clone of Chinese hamster ovary cells …