A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates
L Kari, WM Whitmire, N Olivares-Zavaleta… - Journal of Experimental …, 2011 - rupress.org
Blinding trachoma is an ancient neglected tropical disease caused by Chlamydia
trachomatis for which a vaccine is needed. We describe a live-attenuated vaccine that is …
trachomatis for which a vaccine is needed. We describe a live-attenuated vaccine that is …
CD8+ T cells define an unexpected role in live-attenuated vaccine protective immunity against Chlamydia trachomatis infection in macaques
N Olivares-Zavaleta, WM Whitmire, L Kari… - The Journal of …, 2014 - journals.aai.org
Trachoma, caused by the obligate intracellular organism Chlamydia trachomatis, is the
world's leading cause of preventable blindness for which a vaccine is needed. We have …
world's leading cause of preventable blindness for which a vaccine is needed. We have …
Trachoma: Protective and Pathogenic Ocular Immune Responses to Chlamydia trachomatis
VH Hu, MJ Holland, MJ Burton - PLoS neglected tropical diseases, 2013 - journals.plos.org
Trachoma, caused by Chlamydia trachomatis (Ct), is the leading infectious blinding disease
worldwide. Chronic conjunctival inflammation develops in childhood and leads to eyelid …
worldwide. Chronic conjunctival inflammation develops in childhood and leads to eyelid …
[HTML][HTML] Towards a safe and effective chlamydial vaccine: lessons from the eye
DCW Mabey, V Hu, RL Bailey, MJ Burton, MJ Holland - Vaccine, 2014 - Elsevier
As well as being the most common bacterial sexually transmitted infection, Chlamydia
trachomatis (Ct) is the leading infectious cause of blindness. The pathogenesis of ocular …
trachomatis (Ct) is the leading infectious cause of blindness. The pathogenesis of ocular …
Demonstration of chlamydial RNA and DNA during a culture-negative state
SM Holland, AP Hudson, L Bobo… - Infection and …, 1992 - Am Soc Microbiol
Trachoma is a common blinding disease of humans caused by ocular infections with
Chlamydia trachomatis. The cynomolgus monkey is a valuable primate model for the …
Chlamydia trachomatis. The cynomolgus monkey is a valuable primate model for the …
A chlamydial major outer membrane protein extract as a trachoma vaccine candidate.
PURPOSE: As shown in infected humans and in animal models of chlamydial infection, the
major outer membrane protein (MOMP) of Chlamydia trachomatis is immunogenically …
major outer membrane protein (MOMP) of Chlamydia trachomatis is immunogenically …
The potential for vaccine against infection of the genital tract with Chlamydia trachomatis
JT GRAYSTON, SANPIN WANG - Sexually transmitted diseases, 1978 - JSTOR
THE IMPORTANCE of Chlamydia trachomatis in infections and diseases of the genital tract
is becoming increasingly evident. 1-3 To our knowledge there are no data on the use of C …
is becoming increasingly evident. 1-3 To our knowledge there are no data on the use of C …
Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission-blocking …
L Kari, WM Whitmire, DD Crane… - The Journal of …, 2009 - journals.aai.org
A vaccine is likely the most effective strategy for controlling human chlamydial infections.
Recent studies have shown immunization with Chlamydia muridarum major outer …
Recent studies have shown immunization with Chlamydia muridarum major outer …
Overview of Chlamydia trachomatis Infection and the Requirements for a Vaccine
J Schachter - Reviews of infectious diseases, 1985 - academic.oup.com
Chlamydia trachomatis is an important human pathogen. The development of vaccines
designed to prevent C. trachomatis-associated morbidity would be highly desirable. In the …
designed to prevent C. trachomatis-associated morbidity would be highly desirable. In the …
Transcriptional profiling of human epithelial cells infected with plasmid-bearing and plasmid-deficient Chlamydia trachomatis
SF Porcella, JH Carlson, DE Sturdevant… - Infection and …, 2015 - Am Soc Microbiol
Chlamydia trachomatis is an obligate intracellular epitheliotropic bacterial pathogen of
humans. Infection of the eye can result in trachoma, the leading cause of preventable …
humans. Infection of the eye can result in trachoma, the leading cause of preventable …