Aging is a universal biological process that increases the risk of multiple diseases including
cancer. Growing evidence shows that alterations in the genome and epigenome, driven by …

Cancer is an age-related disease, as incidence and mortality for most types of cancer
increase with age. However, how molecular alterations in tumors differ among patients of …

Older age is a strong risk factor for several diseases, including cancer. The etiology and
biology of age-associated differences among cancers are poorly understood. To address …

The incidence of cancer, adjusted for secular trends, is directly related to age, and advanced
chronologic age is one of the most significant risk factors for cancer. Organismal aging is …

There is increasing support for the idea that aging and cancer are intimately connected by
the activity of specific genes and the cellular responses to potentially oncogenic insults. This …

Aging is the major determinant of cancer incidence, which, in turn, is likely dictated in large
part by processes that influence the progression of early subclinical (occult) cancers …

Cancer is an age‐related disease in organisms with renewable tissues. A malignant tumor
arises in part from genomic damage, which can also drive age‐related degeneration …

Age is the major risk factor in the incidence of cancer, a hyperplastic disease associated with
aging. Here, we discuss the complex interplay between mechanisms underlying aging and …

The ageing of populations worldwide is leading to an unprecedented increase in cancer
cases and fatalities. Understanding the links between cancer and ageing is therefore more …

Evidence shows that there is a synergistic, bidirectional association between cancer and
aging with many shared traits. Age itself is a risk factor for the onset of most cancers, while …