Background In this so-called treat-all era, antiretroviral therapy (ART) interruptions contribute
to an increasing proportion of HIV infections and deaths. Many strategies to improve …

Objective: EMOD-HIV v0. 8 has been used to estimate the potential impact of expanding
treatment guidelines to allow earlier initiation of antiretroviral therapy (ART) in sub-Saharan …

Background New WHO guidelines recommend initiation of antiretroviral therapy for HIV-
positive adults with CD4 counts of 500 cells per μL or less, a higher threshold than was …

The rapid scale-up of antiretroviral therapy (ART) has been one of the great achievements of
global health in the last decade. Declines in deaths from human immunodeficiency virus …

Background Widespread HIV screening and access to highly active antiretroviral treatment
(ART) were cost effective in mathematical models, but population-level implementation has …

Objectives Attrition from care among HIV infected patients can lead to poor clinical
outcomes. Our objective was to evaluate hypothetical interventions seeking to improve …

Abstract Introduction By 2020, 90% of all people diagnosed with HIV should receive long‐
term combination antiretroviral therapy (ART). In sub‐Saharan Africa, this target is …

Background Many mathematical models have investigated the impact of expanding access
to antiretroviral therapy (ART) on new HIV infections. Comparing results and conclusions …

Background. We sought to quantify the survival benefits attributable to antiretroviral therapy
(ART) in South Africa since 2004. Methods. We used the Cost-Effectiveness of Preventing …

Background The number of patients in need of second-line antiretroviral drugs is increasing
in sub-Saharan Africa. We aimed to project the need of second-line antiretroviral therapy in …