The term inflammatory bowel disease (IBD) refers principally to two major categories of
chronic relapsing inflammatory intestinal disorders: Crohn's disease (CD) and ulcerative …

Background The natural course of Crohn's disease is characterized by flare‐ups altered with
periods of remission. The majority of Crohn's disease patients need surgery within 10 years …

Summary Background Patients with Crohn's disease alternate between periods of active,
symptomatic disease and periods of remission. The treatment goal for Crohn's disease is to …

Importance Crohn disease, a chronic gastrointestinal inflammatory disease, is increasing in
incidence and prevalence in many parts of the world. Uncontrolled inflammation leads to …

BACKGROUND The worldwide epidemiology of inflammatory bowel disease (IBD) is rapidly
changing. Increasing Crohn's disease (CD) and ulcerative colitis (UC) incidence and …

The concept of a 'step-up'or 'top-down'approach to the treatment of Crohn's disease has
evolved from the impact of novel anti-TNF (anti-tumour necrosis factor) therapies that have …

The treatment of Crohn's disease is in evolution. Historically, patients were treated based on
clinical symptoms. Today we understand that clinical symptoms correlate poorly with the …

CrohnÕs disease and ulcerative colitis are chronic inflammatory diseases of the
gastrointestinal tract, primarily affecting the small intestine and colon. Although many current …

This review provides a summary of the global epidemiology of inflammatory bowel diseases
(IBD). It is now clear that IBD is increasing worldwide and has become a global emergence …

Crohn's disease is a chronic inflammatory, relapsing-remitting, and progressive
gastrointestinal disorder with an often-negative impact on the physical, emotional, and …