The main targets of hepatitis C virus (HCV) are hepatocytes, the highly polarized cells of the
liver, and all the steps of its life cycle are tightly dependent on host lipid metabolism. The …

Hepatitis C virus (HCV) infects hepatocytes, polarized cells in the liver. Chronic HCV
infection often leads to steatosis, fibrosis, cirrhosis and hepatocellular carcinoma, and it has …

The primary reservoir for hepatitis C virus (HCV) replication is believed to be hepatocytes,
which are highly polarized with tight junctions (TJ) separating their basolateral and apical …

Hepatitis C virus (HCV) primarily infects hepatocytes, which are highly polarized cells. The
relevance of cell polarity in the HCV life cycle has been addressed only in distantly related …

Hepatocytes, the major epithelial cells in the liver, are highly polarized. Their plasma
membranes are separated by tight junctions into sinusoidal–basolateral and canalicular …

BACKGROUND & AIMS: Apicobasal polarity, which is essential for epithelial structure and
function, is targeted by several tumour-related pathogens and is generally perturbed in the …

Attachment of hepatitis C virus (HCV) core protein to lipid droplets (LDs) is linked to release
of infectious progeny from infected cells. Core progressively coats the entire LD surface from …

Hepatitis B virus (HBV)-encoded X protein (HBx) plays an important role in the development
of hepatocellular carcinoma (HCC). The protein SH2 domain containing inositol 5 …

Hepatocytes, like other epithelia, are situated at the interface between the organism's
exterior and the underlying internal milieu and organize the vectorial exchange of …

BACKGROUND & AIMS: Hepatitis C virus (HCV) infection leads to progressive liver disease,
frequently culminating in fibrosis and hepatocellular carcinoma. The mechanisms underlying …