Background and Methods Laboratory, clinical, and epidemiologic evidence suggests that
calcium may help prevent colorectal adenomas. We conducted a randomized, double-blind …

Experimental and observational findings suggest that calcium intake may protect against
colorectal neoplasia. To investigate this hypothesis, we conducted a randomized, double …

Background Calcium supplementation has been shown to decrease the risk of recurrence of
colorectal adenomas in randomized trials. However, the duration of this protective effect after …

Background: Clinical trials have shown that calcium supplementation modestly decreases
the risk of colorectal adenomas. However, few studies have examined the effect of calcium …

The results of three small clinical trials examining the effect of calcium carbonate
supplementation on the proliferation cytokinetics of the rectal epithelium in subjects with a …

Background: Calcium has been hypothesized to reduce the risk of colon cancer, and in a
recent randomized trial, calcium supplementation was associated with reduction in the risk …

BACKGROUND Colorectal adenomas are neoplastic growths that are important targets for
chemoprevention. Dietary calcium is thought to play an important role in chemoprevention …

Background Colonic epithelial cell proliferation is increased in patients at high risk for colon
cancer. Calcium administration has ameliorated the proliferative changes in rodents, and …

Background: The kinetics of colorectal epithelial cell proliferation is altered in patients at
increased risk for colon cancer. Calcium administration ameliorates such proliferative …

Background Some epidemiological studies have suggested that high dietary intake of
calcium and fibre reduces colorectal carcinogenesis. Available data are not sufficient to …