Osteomyelitis is a difficult-to-treat infectious disease. Treatment, which includes controlling
the infection and removing necrotic tissues, is challenging. Considering the side effects and …

Osteomyelitis characterized by an inflammatory response often leads to bone loss and the
spread of bacterial infection to surrounding soft tissues. To overcome the side effects …

Bone infections are a serious problem to cure, as systemic administration of antibiotics is not
very effective due to poor bone vascularization. Therefore, many drug delivery systems are …

Purpose Osteomyelitis, particularly chronic osteomyelitis, remains a major challenge for
orthopedic surgeons. The traditional treatment for osteomyelitis, which involves antibiotics …

In this study, an injectable thermoresponsive hydroxypropyl guar-graft-poly (N-
vinylcaprolactam)(HPG-g-PNVCL) copolymer was synthesized by graft polymerization. The …

Infection of the bone (osteomyelitis) remains one of the most challenging problems in the
field of orthopedic surgery. The limitations of systemic antibiotics administration include …

Background Vancomycin (VAN) is effective in inhibiting inflammatory reactions in chronic
osteomyelitis (CO), while nano-hydroxyapatite (nHA) can effectively address the poor …

Thermosensitive hydrogels are renowned carriers that are used to deliver a variety of drugs
with the aim of combating diseases. In this study, the injectability of thermosensitive …

Osteomyelitis is a bone infection disease which is caused by bacteria or other germs, and
could cause serious impact on the health and working capacity of the patients. Alendronate …

Infection spreading in the skeletal system leading to osteomyelitis can be prevented by the
prolonged administration of antibiotics in high doses. However systemic antibiotherapy …