Novel curcumin-loaded magnetic nanoparticles for pancreatic cancer treatment

MM Yallapu, MC Ebeling, S Khan, V Sundram… - Molecular cancer …, 2013 - AACR
Curcumin (CUR), a naturally occurring polyphenol derived from the root of Curcuma longa,
has showed potent anticancer and cancer prevention activity in a variety of cancers …

Curcumin-loaded magnetic nanoparticles for breast cancer therapeutics and imaging applications

MM Yallapu, SF Othman, ET Curtis… - International journal …, 2012 - Taylor & Francis
Background The next generation magnetic nanoparticles (MNPs) with theranostic
applications have attracted significant attention and will greatly improve nanomedicine in …

Pluronic stabilized Fe 3 O 4 magnetic nanoparticles for intracellular delivery of curcumin

KC Barick, SL Gawali, A Sarkar, A Kunwar… - RSC …, 2016 - pubs.rsc.org
Pluronic stabilized Fe3O4 magnetic nanoparticles (PSMNPs) were developed by
introducing amphiphilic tri-block co-polymer, Pluronic P123 onto the surface of hydrophobic …

Superparamagnetic iron oxide nanoparticles of curcumin enhance gemcitabine therapeutic response in pancreatic cancer

S Khan, S Setua, S Kumari, N Dan, A Massey… - Biomaterials, 2019 - Elsevier
Pancreatic cancer is a complex disease accounting for fibrotic tumors and an aggressive
phenotype. Gemcitabine (GEM) is used as a standard therapy, which develops …

Evaluation of multilayer coated magnetic nanoparticles as biocompatible curcumin delivery platforms for breast cancer treatment

M Akrami, M Khoobi, M Khalilvand-Sedagheh… - RSC Advances, 2015 - pubs.rsc.org
Biocompatible multi-layer iron oxide magnetic nanoparticles (MNPs) for drug delivery
applications with increased loading capacity, sustained sensitive release profile, and high …

Magnetic nanoparticles decorated with PEGylated curcumin as dual targeted drug delivery: Synthesis, toxicity and biocompatibility study

M Ayubi, M Karimi, S Abdpour, K Rostamizadeh… - Materials Science and …, 2019 - Elsevier
The problems associated with hydrophobic anticancer drugs are among the most important
challenges to achieve efficient therapeutics for cancer treatment. In this study, PEGylated …

Breast cancer suppression by curcumin-naringenin-magnetic-nano-particles: In vitro and in vivo studies

MA Askar, OE El Shawi, NA Mansour… - Tumor …, 2021 - content.iospress.com
BACKGROUND: The limitations of surgery, radiotherapy, and chemotherapy in cancer
treatment and the increase in the application of nanomaterials in the field of biomedicine …

Magnetic alginate/chitosan nanoparticles for targeted delivery of curcumin into human breast cancer cells

W Song, X Su, DA Gregory, W Li, Z Cai, X Zhao - Nanomaterials, 2018 - mdpi.com
Curcumin is a promising anti-cancer drug, but its applications in cancer therapy are limited,
due to its poor solubility, short half-life and low bioavailability. In this study, curcumin loaded …

pH triggered curcumin release and antioxidant activity of curcumin loaded γ-Fe2O3 magnetic nanoparticles

PB Patil, SB Parit, PP Waifalkar, SP Patil, TD Dongale… - Materials Letters, 2018 - Elsevier
Curcumin is a proven antioxidant and anti-cancerous compound found in Curcuma longa.
However, the low solubility of curcumin limits its usefulness in therapeutics. To make …

Enhanced accumulation of curcumin and temozolomide loaded magnetic nanoparticles executes profound cytotoxic effect in glioblastoma spheroid model

F Dilnawaz, SK Sahoo - European Journal of Pharmaceutics and …, 2013 - Elsevier
Glioblastomas (GBMs) are highly lethal primary brain tumours. Treatment of these malignant
gliomas remains ineffective as these are extremely resistant to chemotherapeutic …