Cleidocranial dysplasia (CCD) is a rare autosomal dominant disorder caused by mutations
in the Runx2 gene. The CCD is characterized by frontal bossing, a patent anterior fontanelle …

Background Cleidocranial dysplasia (CCD) is a rare congenital autosomal dominant
skeletal disorder. The disorder is caused by heterozygosity of mutations in human RUNX2 …

Cleidocranial dysplasia (CCD) is an autosomal dominant skeletal dysplasia characterised
by abnormal clavicles, patent sutures and fontanelles, supernumerary teeth, short stature …

Discussion More than 500 cases of CCD have been described in the literature and
manifestations vary greatly between individuals (Mundlos, 1999; Golan et al., 2000). The …

Abstract Cleidocranial dysplasia (CCD, MIM 119600) is a rare autosomal dominant disorder
affecting bone, cartilage, craniofacial growth, and tooth formation leading to supernumerary …

Cleidocranial dysplasia (CCD) is a rare autosomal dominant disorder characterized by
skeletal and dental abnormalities primarily, short stature, aplasia or hypoplasia of clavicles …

Cleidocranial dysplasia (CCD), an autosomal dominant disorder with a prevalence of 1 in
1,000,000 individuals, is mainly caused by mutations in Runx2, a gene required for …

Cleidocranial dysplasia (CCD) is a rare hereditary disorder characterized by skeletal
malformations and dental abnormalities. Mutations of the transcription factor RUNX2 are …

Abstract Cleidocranial dysplasia (CCD)(OMIM 119600) is a rare dysplasia of osseous and
dental tissue. Characteristic features are typical facial and dental appearance plus …

Cleidocranial dysplasia (CCD) is an uncommon, generalized skeletal disorder characterized
by delayed ossification of the skull, aplastic or hypoplastic clavicles, and serious, complex …