The growing impact of catalysis in the pharmaceutical industry

CA Busacca, DR Fandrick, JJ Song… - Advanced Synthesis …, 2011 - Wiley Online Library
Catalysis has become increasingly important for the pharmaceutical industry. Catalysis is a
critical technology that enables economical and environmentally‐sound manufacturing …

[图书][B] Applications of transition metal catalysis in drug discovery and development: an industrial perspective

ML Crawley, BM Trost - 2012 - Wiley Online Library
Designing structure for function is a key activity of a chemist approaching problems in fields
ranging from material science to medicine. A critical aspect of such an endeavor is the ability …

Recent advances in developing chemoenzymatic processes for active pharmaceutical ingredients

Junhua, L Zhao, N Ran - Organic process research & development, 2007 - ACS Publications
Biocatalysis is becoming a transformational technology for chemical synthesis as a result of
recent advances in large-scale DNA sequencing, structural biology, protein expression, high …

A pharmaceutical industry perspective on sustainable metal catalysis

JD Hayler, DK Leahy, EM Simmons - Organometallics, 2018 - ACS Publications
As companies grow ever more mindful of the sustainability aspects of their products and
supply chains, an increasing focus on the environmental impact of pharmaceutical …

Organocatalytic synthesis of drugs and bioactive natural products

R Marcia de Figueiredo… - European Journal of …, 2007 - Wiley Online Library
Catalytic reactions are a key element in the design of sustainable chemical processes. As
witnessed in the field of transition metal‐catalysed processes, only those reactions that are …

[图书][B] Non-Noble Metal Catalysis: Molecular Approaches and Reactions

RJMK Gebbink, ME Moret - 2019 - books.google.com
An expert overview of current research, applications, and economic and environmental
advantages The study and development of new homogeneous catalysts based on first-row …

[图书][B] Biocatalysis for the pharmaceutical industry: discovery, development, and manufacturing

JA Tao, GQ Lin, A Liese - 2009 - books.google.com
Biocatalysis is rapidly evolving into a key technology for the discovery and production of
chemicals, especially in the pharmaceutical industry, where high yielding chemo-, regio …

Biocatalysis: A pharma perspective

JP Adams, MJB Brown… - Advanced Synthesis …, 2019 - Wiley Online Library
Biocatalysis over the past few years has matured into an essential tool for modern, cost
effective and sustainable pharmaceutical manufacturing. While some reaction classes are …

On the development of new biocatalytic processes for practical pharmaceutical synthesis

GW Huisman, SJ Collier - Current opinion in chemical biology, 2013 - Elsevier
Biocatalysis has established itself as a scalable and green technology for the production of a
broad range of pharmaceutical APIs and intermediates. The number and scope of …

Extending the application of biocatalysis to meet the challenges of drug development

PN Devine, RM Howard, R Kumar… - Nature Reviews …, 2018 - nature.com
The pharmaceutical industry, driven by an increasing need to deliver new and more effective
medicines to patients, is increasingly turning to the use of engineered biocatalysts for both …