Advances in next generation sequencing technologies, as well as their expanded
accessibility and clinical use over the past 2 decades, have led to an exponential increase in …

Chronic urticaria and angioedema are diseases often managed by Allergy and Immunology
specialists. Recent international guidelines have outlined a stepwise approach to …

Due to marked heterogeneity of clinical presentations, comprehensive knowledge of
angioedema phenotypes is crucial for correct diagnosis and choosing the appropriate …

Urticaria is a common condition that presents with transient, pruritic wheals, angioedema or
both. It often leads to a reduced quality of life and significant socioeconomic burden …

Hereditary angioedema (HAE) poses diagnostic challenges due to its episodic, non-specific
symptoms and overlapping conditions. This study focuses on the genetic basis of HAE …

Several recent practice guidelines have produced consensus differential diagnosis schemes
for urticaria and angioedema with input from both US and European investigators. 1–5 The …

Urticaria and angioedema are experienced by up to 1 in 5 people, usually the result of
common allergen or medication triggers and infections. Similarly, the majority of recurrent …

Chronic spontaneous urticaria (CSU) is primarily a T2-dominant disease with a complex
genetic background. Skin mast cell activation can be induced not only via the IgE-FcεRI axis …

Recurrent angioedema (AE) without wheals is increasingly recognized as a clinical entity
and a frequent cause of admission to the emergency room. The Hereditary Angioedema …

Urticaria (hives) is a common disorder that often presents with angioedema (swelling that
occurs beneath the skin). It is generally classified as acute or chronic. Second-generation …