Exploring the molecular features and genetic prognostic factors of pulmonary high-grade neuroendocrine carcinomas

H Wang, L Yan, Y Zhu, W Sun, X Yang, X Liu, K Chi… - Human Pathology, 2023 - Elsevier
Molecular research on large-cell neuroendocrine carcinoma (LCNEC) and small-cell lung
cancer (SCLC) has progressed significantly. However, there are still fewer molecular …

[HTML][HTML] Update on large cell neuroendocrine carcinoma

K Hiroshima, M Mino-Kenudson - Translational lung cancer …, 2017 - ncbi.nlm.nih.gov
High-grade neuroendocrine carcinomas of the lung are classified into two categories: large
cell neuroendocrine carcinoma (LCNEC) and small cell lung carcinoma (SCLC). While …

[HTML][HTML] Molecular pathology of pulmonary large cell neuroendocrine carcinoma: novel concepts and treatments

M Yoshimura, K Seki, A Bychkov, J Fukuoka - Frontiers in Oncology, 2021 - frontiersin.org
Pulmonary large cell neuroendocrine carcinoma (LCNEC) is an aggressive neoplasm with
poor prognosis. Histologic diagnosis of LCNEC is not always straightforward. In particular, it …

Genomic and immunologic characterization of large-cell neuroendocrine carcinoma of the lung.

C Kim, JE McGrath, J Xiu, M Nagasaka, PC Ma… - 2021 - ascopubs.org
8535 Background: Large-cell neuroendocrine carcinoma (LCNEC) is a rare type of lung
cancer with a poor prognosis. Due to its rarity, molecular characterization of LCNEC is not …

Next-generation sequencing of pulmonary large cell neuroendocrine carcinoma reveals small cell carcinoma–like and non–small cell carcinoma–like subsets

N Rekhtman, MC Pietanza, MD Hellmann… - Clinical Cancer …, 2016 - AACR
Purpose: Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a highly aggressive
neoplasm, whose biologic relationship to small cell lung carcinoma (SCLC) versus non …

[HTML][HTML] Molecular characterization and prognostication of large cell neuroendocrine carcinoma and large cell carcinoma

Y Chen, X Cui, D Wang, G Xia, M Xing, L Cheng… - Frontiers in …, 2022 - frontiersin.org
Purpose Large cell neuroendocrine carcinoma (LCNEC) and classic large cell carcinoma
(LCC) are two distinct entities with different histological and biological characteristics …

Pulmonary large cell neuroendocrine carcinoma (LCNEC): a population-based study addressing recent molecular-genetic advances and emerging therapeutic …

J Khan, AQK Yasinzai, S Matosz, M Khan… - Clinical and …, 2023 - Springer
Background Large cell neuroendocrine carcinoma (LCNEC) of the lung is a rare, aggressive
cancer most commonly found in the lungs but not exclusively, with a worse prognosis than …

Genomic profiling of large-cell neuroendocrine carcinoma of the lung

T Miyoshi, S Umemura, Y Matsumura, S Mimaki… - Clinical Cancer …, 2017 - AACR
Purpose: Although large-cell neuroendocrine carcinoma (LCNEC) of the lung shares many
clinical characteristics with small-cell lung cancer (SCLC), little is known about its molecular …

[HTML][HTML] New molecular classification of large cell neuroendocrine carcinoma and small cell lung carcinoma with potential therapeutic impacts

S Lantuejoul, L Fernandez-Cuesta… - … lung cancer research, 2020 - ncbi.nlm.nih.gov
Large cell neuroendocrine carcinoma (LCNECs) and small cell lung carcinomas (SCLCs)
are high-grade neuroendocrine carcinomas of the lung with very aggressive behavior and …

[HTML][HTML] Diagnosis and molecular profiles of large cell neuroendocrine carcinoma with potential targets for therapy

H Popper, L Brcic - Frontiers in Oncology, 2021 - frontiersin.org
Large cell neuroendocrine carcinoma (LCNEC) together with small cell carcinoma (SCLC)
and typical and atypical carcinoids form the group of pulmonary neuroendocrine tumors …