Expert recommendations for the management of tumor surveillance in children with a variety
of cancer predisposition syndromes (CPS) are available. We aimed (1) at identifying and …

It is estimated that at least 8% to 10% of children diagnosed with cancer have an inherited
cancer predisposition syndrome. Pediatricians may be called upon to (1) identify children …

Advances in the understanding of cancer predisposition and implementation of standardized
cancer surveillance protocols have improved the outcome for certain patients. Future …

Cancer predisposition syndromes (CPS), or genetic syndromes leading to increased cancer
risk, are responsible for at least 10% of all childhood cancers. With advances in both tumor …

Introduction Genetic disposition is a major etiologic factor in childhood cancer. More than
100 cancer predisposing syndromes (CPS) are known. Surveillance protocols seek to …

Approximately 10% of children with newly diagnosed cancer have a cancer predisposition
syndrome (CPS). The optimal diagnostic approach to identify them among children …

At least 10% of children with cancer harbor a disease-associated pathogenic variant in a
known cancer predisposition gene. It is widely accepted that pathogenic variants affecting …

Importance Pediatric oncology patients are increasingly recognized as having an underlying
cancer predisposition syndrome (CPS). Surveillance is often recommended to detect new …

Significant strides have been made in cancer surveillance for children with hereditary cancer
predisposition syndromes. A continued emphasis on consensus-driven screening …

In this issue of Pediatric Annals, we endeavored to provide a series of reviews to provide the
general practitioner with a broad overview of the concepts behind precision medicine as it …