PharmVar GeneFocus: CYP2D6
C Nofziger, AJ Turner, K Sangkuhl… - Clinical …, 2020 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly
polymorphic human CYP2D6 gene locus. CYP2D6 genetic variation impacts the metabolism …
polymorphic human CYP2D6 gene locus. CYP2D6 genetic variation impacts the metabolism …
PharmVar GeneFocus: CYP2C19
MR Botton, M Whirl‐Carrillo… - Clinical …, 2021 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele
nomenclature for the polymorphic human CYP2C19 gene. CYP2C19 genetic variation …
nomenclature for the polymorphic human CYP2C19 gene. CYP2C19 genetic variation …
PharmVar GeneFocus: CYP3A5
C Rodriguez‐Antona, JL Savieo… - Clinical …, 2022 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) catalogs star (*) allele nomenclature
for the polymorphic human CYP3A5 gene. Genetic variation within the CYP3A5 gene locus …
for the polymorphic human CYP3A5 gene. Genetic variation within the CYP3A5 gene locus …
PharmVar GeneFocus: CYP2C9
K Sangkuhl, K Claudio‐Campos… - Clinical …, 2021 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele
nomenclature for the polymorphic human CYP2C9 gene. Genetic variation within the …
nomenclature for the polymorphic human CYP2C9 gene. Genetic variation within the …
[HTML][HTML] Frequency of CYP2D6 alleles including structural variants in the United States
AL Del Tredici, A Malhotra, M Dedek, F Espin… - Frontiers in …, 2018 - frontiersin.org
The CYP2D6 gene encodes an enzyme important in the metabolism of many commonly
used medications. Variation in CYP2D6 is associated with inter-individual differences in …
used medications. Variation in CYP2D6 is associated with inter-individual differences in …
Pharmacogenomics of CYP2D6: molecular genetics, interethnic differences and clinical importance
LK Teh, L Bertilsson - Drug metabolism and pharmacokinetics, 2012 - jstage.jst.go.jp
CYP2D6 has received intense attention since the beginning of the pharmacogenetic era in
the 1970s. This is because of its involvement in the metabolism of more than 25% of the …
the 1970s. This is because of its involvement in the metabolism of more than 25% of the …
Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and …
KE Caudle, K Sangkuhl, M Whirl‐Carrillo… - Clinical and …, 2020 - Wiley Online Library
Translating CYP 2D6 genotype to metabolizer phenotype is not standardized across clinical
laboratories offering pharmacogenetic (PGx) testing and PGx clinical practice guidelines …
laboratories offering pharmacogenetic (PGx) testing and PGx clinical practice guidelines …
[HTML][HTML] Multi-site investigation of strategies for the clinical implementation of CYP2D6 genotyping to guide drug prescribing
LH Cavallari, SL Van Driest, CA Prows, JR Bishop… - Genetics in …, 2019 - Elsevier
Purpose A number of institutions have clinically implemented CYP2D6 genotyping to guide
drug prescribing. We compared implementation strategies of early adopters of CYP2D6 …
drug prescribing. We compared implementation strategies of early adopters of CYP2D6 …
[HTML][HTML] A Review of the Important Role of CYP2D6 in Pharmacogenomics
C Taylor, I Crosby, V Yip, P Maguire, M Pirmohamed… - Genes, 2020 - mdpi.com
Cytochrome P450 2D6 (CYP2D6) is a critical pharmacogene involved in the metabolism of~
20% of commonly used drugs across a broad spectrum of medical disciplines including …
20% of commonly used drugs across a broad spectrum of medical disciplines including …