In postnatal muscle, skeletal muscle precursors (myoblasts) can be derived from satellite
cells (reserve cells located on the surface of mature myofibers) or from cells lying beyond the …

Recent discoveries have demonstrated the extraordinary plasticity of tissue‐derived stem
cells, raising fundamental questions about cell lineage relationships and suggesting the …

The proper functioning of tissues and organs depends on their ability to self-renew and
repair. Some of the tissues, like epithelia, renew almost constantly while in the others this …

Importance of the field: Mesenchymal adult stem cells have properties that make them
attractive for use in tissue engineering and regenerative medicine. They are inherently …

In the vertebrate embryo, skeletal muscle originates from somites and is formed in discrete
steps by different classes of progenitor cells. After myotome formation, embryonic myoblasts …

▪ Abstract This review surveys a wide range of cellular and molecular approaches to
strengthening the injured or weakened heart, focusing on strategies to replace …

Skeletal muscle regeneration in adults is thought to occur through the action of myogenic
satellite cells located in close association with mature muscle fibers; however, these …

Human skeletal muscle contains an accessible adult stem-cell compartment in which
differentiated myofibers are maintained and replaced by a self-renewing stem cell pool …

Three populations of myogenic cells were isolated from normal mouse skeletal muscle
based on their adhesion characteristics and proliferation behaviors. Although two of these …

Cell transplantation is emerging as a new treatment designed to improve the poor outcome
of patients with cardiac failure. Its rationale is that implantation of contractile cells into …