The bioMérieux BIOFIRE Joint Infection (JI) Panel is a multiplex in vitro diagnostic test for the
simultaneous and rapid (~ 1 h) detection of 39 potential pathogens and antimicrobial …

Abstract Background Bone and Joint Infections (BJIs) present with non-specific symptoms
that may include pain, swelling, and fever and are associated with high morbidity and …

Pathogen identification is key in septic arthritis. Culture-based techniques are challenging,
especially when patients have been pretreated with antibiotics or when difficult-to-culture …

Introduction Microbiological diagnosis is central for adequate treatment of bone and joint
infections. Culture-based methods have a limited diagnostic sensitivity and a long …

The diagnosis of periprosthetic joint infection (PJI) is challenging, often requiring multiple
clinical specimens and diagnostic techniques, some with prolonged result turnaround times …

Septic arthritis is a serious condition with significant morbidity and mortality, routinely
diagnosed using culture. The FDA has recently approved the rapid molecular BioFire® Joint …

Introduction: The BIOFIRE Joint Infection (JI) Panel is a diagnostic tool that uses multiplex-
PCR testing to detect microorganisms in synovial fluid specimens from patients suspected of …

Metagenomic shotgun sequencing has the potential to transform how serious infections are
diagnosed by offering universal, culture-free pathogen detection. This may be especially …

Objectives: To evaluate metagenomic next-generation sequencing (mNGS) as a diagnostic
tool in detecting pathogens from osteoarticular infection (OAI) samples. Methods: 130 …

Background: Although microbiological bacterial culture is currently considered the gold
standard for diagnosis of septic arthritis, many studies have documented substantial false …