Periodontal disease is a multifactorial, bacterially induced inflammatory condition
characterized by the progressive destruction of periodontal tissues. The successful …

The impaired differentiation ability of resident cells and disordered immune
microenvironment in periodontitis pose a huge challenge for bone regeneration. Herein, we …

Ideal periosteum materials are required to participate in a sequence of bone repair-related
physiological events, including the initial immune response, endogenous stem cell …

After nearly seven decades of development, dental composite restorations continue to show
limited clinical service. The triggering point for restoration failure is the degradation of the …

Background Most bone-related injuries to grassroots troops are caused by training or
accidental injuries. To establish preventive measures to reduce all kinds of trauma and …

Wound healing from bacterial infections is one of the major challenges in the biomedical
field. The traditional single administration methods are usually accompanied with side …

Bone regeneration remains a critical concern across diverse medical disciplines, because it
is a complex process that requires a combinatorial approach involving the integration of …

Periodontitis is a chronic inflammatory disease initiated by pathogenic biofilms and host
immunity that damages tooth-supporting tissues, including the gingiva, periodontal ligament …

Acute and chronic wounds, caused by trauma, tumors, diabetic foot ulcers, etc., are usually
difficult to heal, while applying exogenous electrical stimulation to enhance the endogenous …

The process of bone repair and regeneration requires multiple physiological cues including
biochemical, electrical and mechanical-that act together to ensure functional recovery …