Biocompatible chitosan based hydrogels for potential application in local tumour therapy

AM Olaru, L Marin, S Morariu, G Pricope… - Carbohydrate …, 2018 - Elsevier
A series of hydrogels based on chitosan polyamine and nitrosalicylaldehyde were prepared
via dynamic covalent chemistry (DCC), by imination and transimination reactions towards …

Injectable hydrogel through hydrophobic grafting on chitosan for controlled drug delivery

AK Mahanta, P Maiti - ACS Applied Bio Materials, 2019 - ACS Publications
An injectable hydrogel of chemically modified chitosan has been developed for controlled
drug delivery application. Highly hydrophilic chitosan is chemically modified through grafting …

Chitosan hydrogels cross-linked with tris (2-(2-formylphenoxy) ethyl) amine: Swelling and drug delivery

AR Karimi, B Rostaminejad, L Rahimi… - International journal of …, 2018 - Elsevier
Abstract Tris (2-(2-formylphenoxy) ethyl) amine was designed and synthesized by reaction
of salicylaldehyde with tris (2-chloroethyl) amine hydrochloride and evaluated as a new …

Chitosan–dipeptide hydrogels as potential anticancer drug delivery systems

J Shim, J Kang, SI Yun - International Journal of Biological Macromolecules, 2021 - Elsevier
A novel chitosan–dipeptide hydrogel was fabricated through a combination of self-assembly
of 9-fluorenylmethoxycarbonyl-modified diphenylalanine (Fmoc–FF) and its electrostatic …

pH-sensitive carboxymethyl chitosan hydrogels via acid-labile ortho ester linkage as an implantable drug delivery system

J Gao, Y Xu, Y Zheng, X Wang, S Li, G Yan… - Carbohydrate …, 2019 - Elsevier
A series of pH-sensitive carboxymethyl chitosan (CMCS) hydrogels were prepared via ortho
ester linkage. DOX-loaded gelatin nanoparticles with an average diameter of around 50 nm …

Porous chitosan hydrogels produced by physical crosslinking: physicochemical, structural, and cytotoxic properties

G Fletes-Vargas, H Espinosa-Andrews… - Polymers, 2023 - mdpi.com
Chitosan hydrogels are biomaterials with excellent potential for biomedical applications. In
this study, chitosan hydrogels were prepared at different concentrations and molecular …

Novel pH-sensitive chitosan-based hydrogel for encapsulating poorly water-soluble drugs

TY Liu, YL Lin - Acta biomaterialia, 2010 - Elsevier
Carboxymethyl–hexanoyl chitosan (CHC) is an amphiphilic chitosan derivative with
excellent swelling ability and water solubility under natural conditions. In this work, the …

Biocompatible poly(N-isopropylacrylamide)-g-carboxymethyl chitosan hydrogels as carriers for sustained release of cisplatin

C Cheng, D Xia, X Zhang, L Chen, Q Zhang - Journal of Materials Science, 2015 - Springer
The therapeutic concentration of cisplatin (CDDP) is usually associated with dose-limiting
side effects. To avoid these harmful effects, a biocompatible hydrogel carrier which …

Physically cross-linked pH-responsive chitosan-based hydrogels with enhanced mechanical performance for controlled drug delivery

YJ Che, D Li, Y Liu, Q Ma, Y Tan, Q Yue, F Meng - RSC advances, 2016 - pubs.rsc.org
A novel physically cross-linked pH-responsive hydrogel with enhanced mechanical
performance (PCAD) was prepared from chitosan (CS), acrylic acid (AA) and (2 …

Cytocompatible Hydrogels Based on Photocrosslinkable Methacrylated O‐Carboxymethylchitosan with Tunable Charge: Synthesis and Characterization

YF Poon, YB Zhu, JY Shen… - Advanced Functional …, 2007 - Wiley Online Library
Ionic hydrogels are attractive for the protection, delivery and controlled release of charged
biomacromolecules such as proteins, growth factors or DNA. We have prepared and …